Understanding LC/MS/MS BlogKnowledge Base Understanding LC/MS/MS The most common bioanalytical method in use today is LC/MS/MS, or liquid chromatography (LC) tandem…CertaraJuly 15, 2014
What Can We Learn from Dose Normalization? BlogKnowledge Base What Can We Learn from Dose Normalization? Dose normalization is a common calculation performed with pharmacokinetic parameters. The general process is to…CertaraMay 19, 2014
Hyperlinking: Making the Most of Navigation in eCTD Submissions Blog Hyperlinking: Making the Most of Navigation in eCTD Submissions When authors generate documents intended for electronic submission they use blue-colored font to indicate where…CertaraFebruary 5, 2014
What is GLP (Good Laboratory Practice)? BlogKnowledge Base What is GLP (Good Laboratory Practice)? Good laboratory practice or GLP is a set of principles intended to assure the quality…CertaraDecember 9, 2013
Understanding Steady State Pharmacokinetics BlogKnowledge Base Understanding Steady State Pharmacokinetics Register for our July 10 webinar and discover fast, flexible, frictionless PK/PD workflows with Phoenix…CertaraNovember 25, 2013
Mean Residence Time (MRT): Understanding How Long Drug Molecules Stay in the Body BlogKnowledge Base Mean Residence Time (MRT): Understanding How Long Drug Molecules Stay in the Body When I first began learning about pharmacokinetics, I was often confused by the mean residence…CertaraMarch 28, 2013
What is a Loading Dose? BlogKnowledge Base What is a Loading Dose? Drug therapy in chronic disease situations requires systemic drug levels to reach target steady-state levels…CertaraMarch 22, 2013
Nonlinear PK: What Does That Mean? BlogKnowledge Base Nonlinear PK: What Does That Mean? You may come across a phrase like the following and wonder what it means: “……CertaraFebruary 17, 2013
Calculating Urine PK Parameters BlogKnowledge Base Calculating Urine PK Parameters Pharmacokinetic analysis normally focuses on systemic exposure to a drug; however, much can be learned…CertaraDecember 6, 2012
Bioavailability BlogKnowledge Base Bioavailability Discover bioavailability in pharmacokinetics, its types, the first-pass effect, and calculations. Explore tools for accurate…CertaraNovember 4, 2012