Simcyp™
Advanced technology solutions support all PBPK applications across drug development
Simcyp PBPK Simulator Version 24 is now available
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Predictive modeling technology across the drug development cycle
PBPK modeling is a mechanistic modeling approach increasingly adopted across all stages of drug development. Simcyp provides a seamless PBPK modeling environment for all stages of drug development, reducing the reliance on extensive in vivo studies.
As the most widely adopted platform for PBPK modeling in drug development, Simcyp is the only technology solution suite developed in collaboration with 37 of the top global pharmaceutical companies over the last 25 years. A testament to its leadership in PBPK, Simcyp is licensed by 11 regulatory agencies worldwide and over 120 novel drugs approved by the FDA used Simcyp in lieu of clinical studies.
PBPK modeling tools for confident decision making
Simcyp offers a comprehensive suite of PBPK modeling solutions, including three flagship platforms: Simcyp PBPK Simulator, Simcyp Biopharmaceutics, and Simcyp Discovery. Together, these solutions provide a seamless modeling environment for PBPK modeling from discovery through post-marketing. In addition, Simcyp is supported by a renowned team of PBPK consultants and scientists globally, ensuring comprehensive and leading-edge support for clients.
- Simcyp PBPK Simulator: the standard for population-based physiologically based modeling and simulation
- Simcyp Biopharmaceutics: advanced PBPK platform for biologic formulation
- Simcyp Discovery: advanced PBPK platform for pre-IND success
Simcyp: Preferred PBPK Platform
11.7% ND
2.6% PK-Sim
5.2% GastroPlus
“Simcyp is the leading platform for PBPK modeling in novel drugs approved by the FDA over the past five years.”
European Journal of Pharmaceutical Sciences
Trusted expertise and proven results
Simcyp's impact on drug development
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Simcyp workshops
Simcyp workshops equip you with the tools to integrate compound-specific in vitro and in vivo data with system-level understanding, enabling precise simulations and predictions of drug behavior across various populations.
Whether you’re preparing Investigational New Drug (IND) applications or refining clinical trial designs, Simcyp workshops are designed to help you improve the quality of your regulatory submissions and achieve better clinical outcomes.
A PBPK modeling platform you can trust
Schedule a demo or consultation to see how Simcyp can empower your team.
Global Impact: Licensed by 11 global regulatory agencies
Discover PBPK applications
Predicting drug performance
Explore how the Simcyp PBPK Simulator accurately predicts drug behavior across diverse patient populations and scenarios.
Drug formulation with Simcyp
Discover advanced PBPK modeling applications to streamline drug formulation and approval using the Simcyp PBPK Simulator.
Developing population files
Learn best practices for creating population files for PBPK modeling with the Simcyp PBPK Simulator.