Quantitative Systems Toxicology Approach Integrates Simcyp PBPK and Core Hepatocyte Metabolism: a Case Study with Valproic Acid Poster Quantitative Systems Toxicology Approach Integrates Simcyp PBPK and Core Hepatocyte Metabolism: a Case Study with Valproic Acid CertaraOctober 16, 2019
Prediction of mAb disposition in hepatic impairment – Evolocumab as a case study Poster Prediction of mAb disposition in hepatic impairment – Evolocumab as a case study CertaraOctober 15, 2019
Use of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model to guide dose adjustments to S-warfarin in different populations Poster Use of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model to guide dose adjustments to S-warfarin in different populations CertaraOctober 15, 2019
Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir® Tablet Absorption in Humans Under Fasted and Fed State Conditions Poster Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir® Tablet Absorption in Humans Under Fasted and Fed State Conditions CertaraOctober 15, 2019
Accounting for CYP2C19 mechanism based inhibition and CYP1A2 induction in a PBPK model for omeprazole Poster Accounting for CYP2C19 mechanism based inhibition and CYP1A2 induction in a PBPK model for omeprazole CertaraOctober 11, 2019
Physiological verification of a geriatric population using the Simcyp R package Poster Physiological verification of a geriatric population using the Simcyp R package CertaraOctober 11, 2019
Estimation of Effective pKa of Bicarbonate Buffer Poster Estimation of Effective pKa of Bicarbonate Buffer CertaraOctober 11, 2019
Quantification of Human Blood-Brain Barrier Transporters in Health and in Dementia by Global and Targeted Proteomics Poster Quantification of Human Blood-Brain Barrier Transporters in Health and in Dementia by Global and Targeted Proteomics CertaraOctober 11, 2019
The Molecular Stethoscope: RNA of Drug Metabolising Enzymes in Circulating Vesicles Correlates with their Specific Protein Content in the Liver Poster The Molecular Stethoscope: RNA of Drug Metabolising Enzymes in Circulating Vesicles Correlates with their Specific Protein Content in the Liver CertaraOctober 11, 2019
Propofol: A Tail of Drug Disposition and Dynamics in Different Dog Breeds Poster Propofol: A Tail of Drug Disposition and Dynamics in Different Dog Breeds CertaraOctober 11, 2019
