Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
This review article examines the development of radiopharmaceutical imaging agents and radioligand therapies for pediatric…
CertaraMarch 26, 2026
Portfolio Prioritization for Large and Small Pharma Using Early-Stage Biosimulation
Learn how early-stage biosimulation and mechanistic modeling enable smarter portfolio prioritization before IND-enabling studies. Watch…
CertaraMarch 25, 2026
An Integrated Nonclinical and Clinical Risk Assessment of the Effects of Investigational ATRi Tuvusertib on QTc Interval in Patients With Solid Tumors
This publication highlights how pharmacometric modeling, supported by Certara, was used to inform dose selection…
CertaraMarch 25, 2026
Model-Based Patient Selection and Dosing Strategies for HRAS and PIK3CA Dysregulated HNSCC: A QSP Model for Alpelisib and Tipifarnib Combination
This study showcases how quantitative systems pharmacology (QSP) and model-informed drug development (MIDD) can transform…
Danielle PillsburyMarch 25, 2026
Right Dose, Right Regimen: Model-Informed Strategies for Antibody–Drug Conjugates (ADCs)
Watch this on-demand webinar to learn how model-informed strategies using PopPK, PBPK, and QSP can…
CertaraMarch 25, 2026
Why the Most Important Phase 3 Decisions Should Be Made Before Phase 3
Learn how advanced modeling for reimbursement strategy using MBMA and QSP strengthens payer evidence and…
CertaraMarch 24, 2026
Population Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Analysis for Clazakizumab in Patients With End-Stage Kidney Disease Undergoing Dialysis
This study evaluated the pharmacokinetics (PK) and pharmacokinetic–pharmacodynamic (PK–PD) relationship of clazakizumab, an anti–interleukin-6 (IL-6)…
Danielle PillsburyMarch 24, 2026
Model-informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis
This article describes how a model-informed drug development (MIDD) approach was used to support the…
CertaraMarch 24, 2026
Regulatory horizons 2026: clinical pharmacology strategy and regulatory expectations
Learn how regulatory expectations in clinical pharmacology are evolving and how to build a strategy…
CertaraMarch 24, 2026
