The Case for Simulating Pregnancy
Pregnant women are routinely excluded from drug trials, leaving clinicians without dosing guidance. Discover how…
CertaraJune 9, 2026
Clinical Validation of a QSP Model for ISB 2001, a Trispecific T Cell Engager to Support Optimal FIH Study Design in RRMM Patients
See how a QSP model guided efficacy-proximal FIH dosing for ISB 2001 in the TRIgnite-1…
CertaraJune 4, 2026
Applying AI-Driven Biosimulation to Drug Discovery
Certara President Leif Pedersen explains how PBPK and QSP modeling, proven across 125+ FDA-approved drugs,…
CertaraJune 2, 2026
Oxford Academic, Neuro-Oncology Pediatrics – BRAF pub: Growth recovery in patients with BRAF-altered pediatric low-grade glioma following treatment with tovorafenib
This publication reports a pooled retrospective analysis evaluating growth patterns in children with B-Raf proto-oncogene…
Dorottya Gui-BodnarMay 28, 2026
The Modeling Advantage: How Forward-Thinking Sponsors Are Moving Faster, De-Risking Earlier, and Winning with Regulators
Learn how PBPK and QSP modeling support regulatory confidence, accelerate drug development, and align with…
CertaraMay 26, 2026
Certainty US 2026 recap: advancing model-informed drug development right from the start
This blog shares the highlights of our US Certainty event and explains how AI-enabled approaches…
CertaraMay 26, 2026
Population Pharmacokinetic Modeling of Niraparib to Assess Different Absorption Models
This publication describes the development of an updated population pharmacokinetic (PopPK) model for niraparib, a…
CertaraMay 21, 2026
Quantitative Systems Pharmacology Modeling of Atopic Dermatitis to Predict Biologic Therapy Response
Quantitative Systems Pharmacology Modeling of Atopic Dermatitis to Predict Biologic Therapy Response
Explore a quantitative systems pharmacology (QSP) model of atopic dermatitis calibrated to clinical trial data.
CertaraMay 21, 2026
How to Leverage PBPK Modeling and Simulation in Drug Research and Development
Learn how PBPK modeling and simulation in drug research and development reduces clinical burden, supports…
CertaraMay 12, 2026
Predicting FcRn-Mediated PK/PD with PBPK Modeling
Learn how PBPK modeling predicts FcRn binder PK/PD and IgG dynamics across species.
CertaraMay 12, 2026
