Optimization of Intestinal Microsomal Preparation in the Rat: A Systematic Approach to Assess the Influence of Various Methodologies on Metabolic Activity and Scaling Factors Publication Optimization of Intestinal Microsomal Preparation in the Rat: A Systematic Approach to Assess the Influence of Various Methodologies on Metabolic Activity and Scaling Factors CertaraApril 1, 2017
The Model-informed Precision Dosing Revolution Is Coming Blog The Model-informed Precision Dosing Revolution Is Coming Modeling and simulation (M&S) has been widely accepted and adopted by biopharmaceutical companies and global…CertaraMarch 7, 2017
CYP2C9 Genotype-dependent Warfarin Pharmacokinetics: Impact of CYP2C9 Genotype on R- and S-Warfarin and Their Oxidative Metabolites Publication CYP2C9 Genotype-dependent Warfarin Pharmacokinetics: Impact of CYP2C9 Genotype on R- and S-Warfarin and Their Oxidative Metabolites CertaraMarch 1, 2017
Biopharmaceutics Data Management System for Anonymized Data Sharing and Curation: First Application with Orbito IMI Project Publication Biopharmaceutics Data Management System for Anonymized Data Sharing and Curation: First Application with Orbito IMI Project CertaraMarch 1, 2017
Prediction of Liver Volume—A Population-based Approach to Meta-analysis of Pediatric, Adult, and Geriatric Populations—An Update Publication Prediction of Liver Volume—A Population-based Approach to Meta-analysis of Pediatric, Adult, and Geriatric Populations—An Update —CertaraMarch 1, 2017
Navigating EMA Policy 0070—How Do We Ensure Compliance? On-Demand Webinar Navigating EMA Policy 0070—How Do We Ensure Compliance? Speaker Lora Killian provides insight on how EMA Policy 0070 will affect your organization and…CertaraFebruary 23, 2017
Application of the MechPeff Model to Predict Passive Effective Intestinal Permeability in the Different Regions of the Rodent Small Intestine and Colon Publication Application of the MechPeff Model to Predict Passive Effective Intestinal Permeability in the Different Regions of the Rodent Small Intestine and Colon CertaraFebruary 1, 2017
The Absorption Kinetics of Ketoconazole Plays a Major Role in Explaining the Reported Variability in the Level of Interaction with Midazolam: Interplay Between Formulation and Inhibition of Gut Wall and Liver Metabolism Publication The Absorption Kinetics of Ketoconazole Plays a Major Role in Explaining the Reported Variability in the Level of Interaction with Midazolam: Interplay Between Formulation and Inhibition of Gut Wall and Liver Metabolism CertaraFebruary 1, 2017
A Pharmacokinetic/Viral Kinetic Model to Evaluate Treatment of Chronic HCV Infection with a Non-nucleoside Polymerase Inhibitor Publication A Pharmacokinetic/Viral Kinetic Model to Evaluate Treatment of Chronic HCV Infection with a Non-nucleoside Polymerase Inhibitor CertaraJanuary 10, 2017
Clarification of Contraceptive Drug Pharmacokinetics in Obesity Publication Clarification of Contraceptive Drug Pharmacokinetics in Obesity CertaraJanuary 1, 2017