Predictive Performance of Caffeine Preterm PBPK Model and Effect of Time-Varying Physiology on Predictions Poster Predictive Performance of Caffeine Preterm PBPK Model and Effect of Time-Varying Physiology on Predictions CertaraOctober 17, 2019
Prediction of Drug-Drug Interaction between Phenobarbital and Theophylline in Children using Physiologically-Based Pharmacokinetic Modelling Poster Prediction of Drug-Drug Interaction between Phenobarbital and Theophylline in Children using Physiologically-Based Pharmacokinetic Modelling CertaraOctober 17, 2019
Development of a PBPK model for the prediction of Amiodarone pharmacokinetics in fed and fasted state using ADAM model Poster Development of a PBPK model for the prediction of Amiodarone pharmacokinetics in fed and fasted state using ADAM model CertaraOctober 17, 2019
The Certara Quantitative Systems Toxicology & Safety (QSTS) Pharma Consortium: Overview and Invitation to Join Poster The Certara Quantitative Systems Toxicology & Safety (QSTS) Pharma Consortium: Overview and Invitation to Join CertaraOctober 17, 2019
Quantitative Systems Toxicology Approach Integrates Simcyp PBPK and Core Hepatocyte Metabolism: a Case Study with Valproic Acid Poster Quantitative Systems Toxicology Approach Integrates Simcyp PBPK and Core Hepatocyte Metabolism: a Case Study with Valproic Acid CertaraOctober 16, 2019
Prediction of mAb disposition in hepatic impairment – Evolocumab as a case study Poster Prediction of mAb disposition in hepatic impairment – Evolocumab as a case study CertaraOctober 15, 2019
Use of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model to guide dose adjustments to S-warfarin in different populations Poster Use of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model to guide dose adjustments to S-warfarin in different populations CertaraOctober 15, 2019
Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir® Tablet Absorption in Humans Under Fasted and Fed State Conditions Poster Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir® Tablet Absorption in Humans Under Fasted and Fed State Conditions CertaraOctober 15, 2019
Accounting for CYP2C19 mechanism based inhibition and CYP1A2 induction in a PBPK model for omeprazole Poster Accounting for CYP2C19 mechanism based inhibition and CYP1A2 induction in a PBPK model for omeprazole CertaraOctober 11, 2019
Physiological verification of a geriatric population using the Simcyp R package Poster Physiological verification of a geriatric population using the Simcyp R package CertaraOctober 11, 2019