VIVD: a Virtual In Vitro Distribution Model for Predicting Intra- and Sub-Cellular Concentrations in Toxicity Assays Poster VIVD: a Virtual In Vitro Distribution Model for Predicting Intra- and Sub-Cellular Concentrations in Toxicity Assays CertaraAugust 29, 2019
On Early Paediatric Study Design: Sample Size Calculation using a PBPK Approach within the Simcyp Simulator Poster On Early Paediatric Study Design: Sample Size Calculation using a PBPK Approach within the Simcyp Simulator CertaraAugust 29, 2019
Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model Poster Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model CertaraAugust 29, 2019
Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model Poster Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model CertaraAugust 28, 2019
In silico assessment of antiarrhythmic effects of drug ranolazine on electrical activity in human ventricular myocardium Poster In silico assessment of antiarrhythmic effects of drug ranolazine on electrical activity in human ventricular myocardium CertaraAugust 28, 2019
Prediction of Erythropoietin Disposition in a Paediatric Population Using SimCYP® Poster Prediction of Erythropoietin Disposition in a Paediatric Population Using SimCYP® CertaraAugust 28, 2019
An in silico PBPK-PD coupled approach to assess Zolpidem effect on pre-clinically and clinically measured cardiac repolarisation parameters in the absence and presence of a circadian model of plasma ion concentration. Poster An in silico PBPK-PD coupled approach to assess Zolpidem effect on pre-clinically and clinically measured cardiac repolarisation parameters in the absence and presence of a circadian model of plasma ion concentration. CertaraAugust 28, 2019
Repolarisation Rate: an integrative biomarker of cardiac action potential repolarisation Poster Repolarisation Rate: an integrative biomarker of cardiac action potential repolarisation CertaraAugust 28, 2019
Towards unravelling the mechanism of Cardiotoxicity of Citalopram: Utilisation of mechanistic cardiac electrophysiology modelling with Simcyp Cardiac Safety Simulator to explore various hypotheses Poster Towards unravelling the mechanism of Cardiotoxicity of Citalopram: Utilisation of mechanistic cardiac electrophysiology modelling with Simcyp Cardiac Safety Simulator to explore various hypotheses CertaraAugust 28, 2019
Mechanistic modelling of dermal drug absorption using the Simcyp Multi-phase Multi-layer MechDermA model: Case study of a transdermal patch formulation of weak base drug timolol Poster Mechanistic modelling of dermal drug absorption using the Simcyp Multi-phase Multi-layer MechDermA model: Case study of a transdermal patch formulation of weak base drug timolol CertaraAugust 28, 2019
