Strengths and opportunities for HTAs and market access in Europe through case studies On-Demand Webinar Strengths and opportunities for HTAs and market access in Europe through case studies Amongst the real world data sources in Europe, the French Healthcare database SNDS is the…CertaraMay 26, 2021
Mechanistic quantitative pharmacology strategies for the early clinical development of bispecific antibodies in oncology Publication Mechanistic quantitative pharmacology strategies for the early clinical development of bispecific antibodies in oncology Bispecific antibodies (bsAbs) have become an integral component of the therapeutic research strategy to treat…CertaraJuly 14, 2020
Development of Paclitaxel PBPK Model to Predict Tumour Concentration in Cancer Patients Poster Development of Paclitaxel PBPK Model to Predict Tumour Concentration in Cancer Patients CertaraJune 24, 2019
Mechanistic models of cancer Mechanistic models cancer-immune cycle and immunotherapies Poster Mechanistic models of cancer Mechanistic models cancer-immune cycle and immunotherapies CertaraJune 24, 2019
Integration of a Tumour Growth Inhibition Model within a Mouse Physiologically-Based Pharmacokinetic Model Poster Integration of a Tumour Growth Inhibition Model within a Mouse Physiologically-Based Pharmacokinetic Model CertaraJune 24, 2019
Optimize Immuno-oncology Drug Discovery and Development Using QSP White Paper Optimize Immuno-oncology Drug Discovery and Development Using QSP A Quantitative Systems Pharmacology (QSP) approach for developing combination immune-oncology therapies can be used to…CertaraJune 19, 2019
Population Pharmacokinetic Analysis of DS-8201a, A HER2-Targeting Antibody-Drug Conjugate, in Patients with HER2-Positive Breast Cancer or Other Solid Tumors Poster Population Pharmacokinetic Analysis of DS-8201a, A HER2-Targeting Antibody-Drug Conjugate, in Patients with HER2-Positive Breast Cancer or Other Solid Tumors CertaraMay 2, 2019
Simulating the Impact of the Interplay Between CYP2C19 Polymorphisms and Ethnicity on Response to Clopidogrel, Using PBPK-PD Models Poster Simulating the Impact of the Interplay Between CYP2C19 Polymorphisms and Ethnicity on Response to Clopidogrel, Using PBPK-PD Models CertaraApril 22, 2019
Exposure-Response Analyses to Support Dose Justification of DS-8201A, A HER2-Targeting Antibody-Drug Conjugate, in HER2-Positive Breast Cancer Patients Poster Exposure-Response Analyses to Support Dose Justification of DS-8201A, A HER2-Targeting Antibody-Drug Conjugate, in HER2-Positive Breast Cancer Patients CertaraApril 22, 2019
Relationship of Ivosidenib Plasma Concentration to Heart Rate-Corrected QT Interval in Patients with IDH1-Mutant Advanced Hematologic Malignancies Poster Relationship of Ivosidenib Plasma Concentration to Heart Rate-Corrected QT Interval in Patients with IDH1-Mutant Advanced Hematologic Malignancies CertaraApril 22, 2019