VIVD: a Virtual In Vitro Distribution Model for Predicting Intra- and Sub-Cellular Concentrations in Toxicity Assays Poster VIVD: a Virtual In Vitro Distribution Model for Predicting Intra- and Sub-Cellular Concentrations in Toxicity Assays CertaraAugust 29, 2019
On Early Paediatric Study Design: Sample Size Calculation using a PBPK Approach within the Simcyp Simulator Poster On Early Paediatric Study Design: Sample Size Calculation using a PBPK Approach within the Simcyp Simulator CertaraAugust 29, 2019
Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model Poster Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model CertaraAugust 29, 2019
Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model Poster Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model CertaraAugust 28, 2019
Simulating the effect of anti-diabetic drugs on ATP-sensitive potassium (KATP) channels inhibition in a human cardiac cell model (ORd) Poster Simulating the effect of anti-diabetic drugs on ATP-sensitive potassium (KATP) channels inhibition in a human cardiac cell model (ORd) CertaraAugust 28, 2019
Prediction of Erythropoietin Disposition in a Paediatric Population Using SimCYP® Poster Prediction of Erythropoietin Disposition in a Paediatric Population Using SimCYP® CertaraAugust 28, 2019
An in silico PBPK-PD coupled approach to assess Zolpidem effect on pre-clinically and clinically measured cardiac repolarisation parameters in the absence and presence of a circadian model of plasma ion concentration. Poster An in silico PBPK-PD coupled approach to assess Zolpidem effect on pre-clinically and clinically measured cardiac repolarisation parameters in the absence and presence of a circadian model of plasma ion concentration. CertaraAugust 28, 2019
Repolarisation Rate: an integrative biomarker of cardiac action potential repolarisation Poster Repolarisation Rate: an integrative biomarker of cardiac action potential repolarisation CertaraAugust 28, 2019
Towards unravelling the mechanism of Cardiotoxicity of Citalopram: Utilisation of mechanistic cardiac electrophysiology modelling with Simcyp Cardiac Safety Simulator to explore various hypotheses Poster Towards unravelling the mechanism of Cardiotoxicity of Citalopram: Utilisation of mechanistic cardiac electrophysiology modelling with Simcyp Cardiac Safety Simulator to explore various hypotheses CertaraAugust 28, 2019
Mechanistic modelling of dermal drug absorption using the Simcyp Multi-phase Multi-layer MechDermA model: Case study of a transdermal patch formulation of weak base drug timolol Poster Mechanistic modelling of dermal drug absorption using the Simcyp Multi-phase Multi-layer MechDermA model: Case study of a transdermal patch formulation of weak base drug timolol CertaraAugust 28, 2019
