Application of mechanistic PBPK modelling to evaluate the power of pharmacogenomics studies using OATP1B1 and rosuvastatin as an example August 28, 2019 By webdev
APPLICATION OF PBPK AND BAYESIAN MODELLING FOR PREDICTION OF THE LIKELIHOOD OF INDIVIDUAL PATIENTS EXPERIENCING SERIOUS ADVERSE REACTIONS TO A STANDARD DOSE OF EFAVIRENZ August 28, 2019 By webdev
THE RELATIONSHIP BETWEEN mRNA AND ACTIVITY FOLLOWING INDUCTION OF CYP3A4 AND CYP2B6 ACROSS A RANGE OF PROTOTYPICAL INDUCERS August 28, 2019 By webdev
DEVELOPMENT OF A PBPK MODEL FOR EFAVIRENZ THAT ACCOUNTS FOR AUTO-INDUCTION AND ITS EFFECT ON THE CYP2B6 SUBSTRATE BUPROPION August 23, 2019 By webdev
Prediction of Prothrombin Time after Oral Administration of S-Warfarin in Different CYP2C9 Phenotypes in Asian and Caucasian populations using the Simcyp Simulator August 23, 2019 By webdev
Prediction of Midazolam Pharmacokinetics in Pregnant Women with Coeliac Disease using Simcyp Pregnancy PBPK Model August 23, 2019 By webdev
Prediction of Midazolam Concentration Profile in Obese Adolescent Population Using Physiologically Based Pharmacokinetic model August 23, 2019 By webdev
Prediction of Enfuvertide Concentration-Time Profile in a Paediatric Population after Parenteral Administration Using a Physiologically Based Pharmacokinetic Model August 23, 2019 By webdev
Simulating the effect of anti-diabetic drugs on ATP-sensitive potassium (KATP) channels inhibition in a human cardiac cell model (ORd) August 23, 2019 By webdev
Establishing an In Vitro-In Vivo Correlation (IVIVC) for Tramadol Extended-Release Tablets : Conventional vs. Physiologically Based IVIVC August 22, 2019 By webdev