Prediction of Erythropoietin Disposition in a Paediatric Population Using SimCYP® August 28, 2019 By webdev
An in silico PBPK-PD coupled approach to assess Zolpidem effect on pre-clinically and clinically measured cardiac repolarisation parameters in the absence and presence of a circadian model of plasma ion concentration. August 28, 2019 By webdev
Repolarisation Rate: an integrative biomarker of cardiac action potential repolarisation August 28, 2019 By webdev
Towards unravelling the mechanism of Cardiotoxicity of Citalopram: Utilisation of mechanistic cardiac electrophysiology modelling with Simcyp Cardiac Safety Simulator to explore various hypotheses August 28, 2019 By webdev
Mechanistic modelling of dermal drug absorption using the Simcyp Multi-phase Multi-layer MechDermA model: Case study of a transdermal patch formulation of weak base drug timolol August 28, 2019 By webdev
Toward Unravelling the Mechanism of Cardiotoxicity of Citalopram: Utilization of Mechanistic Cardiac Electrophysiology Modelling with Simcyp Cardiac Safety Simulator (CSS) to Explore Various Hypotheses August 28, 2019 By webdev
Application of a physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model for prediction of drug-drug interactions (DDIs) involving the JAK1/2 inhibitor Ruxolitinib in Caucasians and Japanese August 28, 2019 By webdev
Evaluating the efficiency of payload delivery by ADCs using a minimal PBPK model August 28, 2019 By webdev
APPLICATION OF A MULTI-COMPARTMENT PERMEABILITY-LIMITED LUNG MODEL TO PREDICT LUNG CONCENTRATIONS OF MOXIFLOXACIN IN VIRTUAL HUMAN SUBJECTS August 28, 2019 By webdev