Certara Products – Simcyp

Learn how Simcyp PBPK modeling established bioequivalence and supported FDA approval of a generic product

Explore how mechanistic surface pH modeling in Simcyp improves PBPK prediction of dissolution-controlled absorption for…

Explore how a mechanistic dermal PBPK model with experimentally scaled, layer-specific skin metabolism predicts propylparaben…

Discover how PBPK modeling with Simcyp mechanistically explains the formulation-dependent negative food effect of trospium…

Discover how sex-dependent within-subject variability in gastric emptying time influences supersaturation, precipitation, and Cmax in…

Explore mechanistic PBPK modelling of itraconazole oral solution, revealing how bile salt–cyclodextrin interactions drive a…