Mechanistic Modeling of Genome Scale Molecular Interaction Networks

Andrzej Kierzek

Upon the completion of the Human Genome Project, the lead investigator, Dr. Francis Collins remarked: Science is a voyage of exploration into the unknown. We are here today to celebrate a milestone along a truly unprecedented voyage, this one into ourselves. Alexander Pope wrote, “Know then thyself. Presume not God to scan. The proper study […]

Read More
Topics: PBPK Modeling & Simulation, Systems Pharmacology

Princeton Workshop: October 2017

Model-informed Drug Development Incorporating population variability into mechanistic prediction of PK and modeling PK-PD October 23–27  in Princeton, NJ Delegates will learn how to simulate: Metabolic drug clearance (CL) Metabolic drug-drug interactions (DDIs) Gut first-pass metabolism Oral drug absorption incorporating food effects and the impact of dosage form Effect of transporters and enterohepatic recirculation on kinetics […]

Read More
Learn More