Modeling and Simulation Archives

Publication

A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk

The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…

CertaraSeptember 18, 2024

Publication

A tutorial on physiologically based pharmacokinetic approaches in lactation research

The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…

CertaraSeptember 16, 2024

Publication

Application of physiologically based pharmacokinetic modeling of novel drugs approved by the U.S. food and drug administration

The article from the European Journal of Pharmaceutical Sciences reviews the role of Physiologically Based…

CertaraSeptember 1, 2024

Publication

Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator

The article "Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system…

CertaraAugust 26, 2024

Publication

Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)

The article “Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL)…

CertaraAugust 26, 2024

Podcast Video

Certara Talks: PAGE 2024

Learn more about our Modeling & Simulation Services Transcript: Hello, and welcome to Certara…

CertaraAugust 5, 2024

Publication

A guide to developing population files for physiologically-based pharmacokinetic modeling in the Simcyp Simulator

This collaborative effort by Certara and the Centre for Applied Pharmacokinetic Research (CAPKR) at The…

CertaraJuly 24, 2024

On-Demand Webinar

Hosted Phoenix for High Performance PK/PD

How do you maximize efficiency in PK/PD analysis and pharmacometric modeling? Well-trained scientists, reproducible workflows,…

CertaraJuly 8, 2024

Publication

A literature review of drug transport mechanisms during lactation

The literature review titled "A literature review of drug transport mechanisms during lactation," authored by…

CertaraJuly 7, 2024

Publication

pyDarwin machine learning algorithms application and comparison in nonlinear mixed-effect model selection and optimization

Dr. Mark Sale, Dr. Keith Nieforth, James Craig and peers from industry, healthcare, and academia…

CertaraJune 28, 2024

Modeling and Simulation

A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk

A tutorial on physiologically based pharmacokinetic approaches in lactation research

Application of physiologically based pharmacokinetic modeling of novel drugs approved by the U.S. food and drug administration

Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator

Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)

Certara Talks: PAGE 2024

A guide to developing population files for physiologically-based pharmacokinetic modeling in the Simcyp Simulator

Hosted Phoenix for High Performance PK/PD

A literature review of drug transport mechanisms during lactation

pyDarwin machine learning algorithms application and comparison in nonlinear mixed-effect model selection and optimization

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