User-friendly and powerful nonlinear mixed effect modeling software
Phoenix NLMETM lets you focus on your models, not the tools required to implement the models. Phoenix NLME is a population modeling and simulation software for scientists with varying levels of experience—from novice PK/PD scientists to the most advanced modelers. This comprehensive package includes integrated data preparation, modeling, and graphics tools with the same user interface that is used in Phoenix WinNonlin™.
18 of the top 20 pharmaceutical companies in the world use Phoenix NLME.
PHOENIX VERSION 8.5.2
Accomplish more with the latest release of the Phoenix platform with:
- Sign-in via Certara Central Administration: Phoenix 8.5 introduces user sign-in via Certara Central Admin, offering Single Sign-On and centralized authentication. This simplifies license management, streamlines assignments, enhances access control, and improves the user experience by providing easier access to resources and support.
- Reporting Enhancements (Tables, Plotting, Reporter): The updates offer increased customization and efficiency in data presentation, along with advancing capabilities for visual data analysis. These improvements streamline the reporting process and enable more detailed and readily interpretable reports.
- NLME (Non-linear mixed effects) Enhancements: Phoenix NLME is a population modeling and simulation software for scientists with varying levels of experience—from novice PK/PD scientists to the most advanced modelers. The update improves the precision of modeling, increases the adaptability for users, and provides tools to enhance the interpretability of models.
- Auto-Repair Feature for Project Files: Phoenix 8.5.2 introduces a powerful new feature that automatically repairs and opens project files that could no longer be opened in previous versions. If any data loss is expected during the repair, Phoenix will notify users and document the details.
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Widely used for regulatory submissions
Phoenix NLME meets all scientific and technical requirements for PK/PD analyses. Because of its flexibility and power, Phoenix NLME is used across drug development phases and for global regulatory submissions, including:
- Translational modeling
- Extrapolation of PK data from animals to humans
- Prediction of the pharmacodynamics in humans based on in vitro models
- Combination of PK and PD data from multiple animal studies
- Enhancement of study designs to minimize animal use
Grid computing and algorithms for faster results
- Includes QRPEM, the fastest expectation maximization algorithm available
- Comes grid-enabled with an algorithm that uses the maximum number of cores for each run to minimize time from days to minutes. Send jobs to a remote computing platform with one click.
- Offers separates analyses for different types of data such as continuous data with BQLs, categorical data, and time to event data with Visual Predictive Check
- Simplifies coding delays in PK/PD models with the distributed delay function, which can be used in place of transit compartments, dual absorption models, effect compartment models, and indirect response models.
Intuitive graphical user interface
- Develop models without coding with our graphical model editor and model library. Advanced users can code using Phoenix Modeling Language (PML)
- Avoid poor parameterization with the graphical tool for initial model parameter estimates
- Quickly troubleshoot issues with diagnostic dialog messages that pinpoint errors
- Compare models side-by-side with the comparer tool
- Automatically generate diagnostic outputs for each model to assess model robustness
Access Phoenix Anywhere!
Phoenix Hosted empowers research teams with enhanced performance and increased flexibility in their daily NLME business. Phoenix Hosted supports various operating systems and hardware and offers easy scalability to adapt to organizational needs. The solution facilitates seamless collaboration on PK projects and, as an added productivity booster, allows extensive processing to occur remotely while users focus on scientific tasks within Phoenix. IT departments also benefit from Phoenix Hosted, as it reduces their workload by eliminating the need for desktop software installation and management.