Clinical Pharmacology Archives

Blog

Key Considerations to Ensure Maximal Probability of Antibody Drug Conjugate Development Success

Antibody drug conjugates (ADC) are a unique way to obliterate tumor cells and represent an…

CertaraJuly 8, 2021

Blog

8 Tips for Successfully Developing Oligonucleotide Therapies

By Eva Gil Berglund and Nathalie H Gosselin Oligonucleotide therapeutics are a validated class of…

CertaraFebruary 1, 2021

White Paper

“Where do I start?”: Strategies for selecting the first dose for human clinical trials

This guide to dose selection for first-in-human studies explains the conceptual framework, methods, and tools…

CertaraDecember 22, 2020

Publication

Metformin Treatment of Type 2 Diabetes Mellitus in Pregnancy: Update on Safety and Efficacy

CertaraApril 25, 2018

Blog

Using M&S to Evaluate Oncology Drug Dosing

There are numerous challenges in developing oncology drugs: (1) they are often very toxic which…

CertaraApril 13, 2018

Blog

Using a Pharmacology to Payer Framework to Support Product Development

Modeling and simulation (M&S) of complex systems has primarily advanced vertically in differing scientific domains…

CertaraMarch 16, 2018

Publication

Cost-utility Analysis of Antiviral Use Under Pandemic Influenza Using a Novel Approach—Linking Pharmacology, Epidemiology and Heath Economics

CertaraMarch 1, 2018

Blog

Surveying the Lay of the Land for Modeling & Simulation for Global Regulatory Submissions

Analogous to how a geologist surveys the “lay of the land” to determine if oil…

CertaraFebruary 16, 2018

Publication

Clinical Pharmacology Tools and Evaluations to Facilitate Comprehensive Dose Finding in Oncology: A Continuous Risk-Benefit Approach

CertaraSeptember 15, 2017

White Paper

Drug Asset Evaluation: Increasing “Probability of Success” of a Deal

Certara’s due diligence/asset evaluation teams are comprised of drug development and commercialization experts who advise…

CertaraAugust 24, 2017

Clinical Pharmacology

Key Considerations to Ensure Maximal Probability of Antibody Drug Conjugate Development Success

8 Tips for Successfully Developing Oligonucleotide Therapies

“Where do I start?”: Strategies for selecting the first dose for human clinical trials

Metformin Treatment of Type 2 Diabetes Mellitus in Pregnancy: Update on Safety and Efficacy

Using M&S to Evaluate Oncology Drug Dosing

Using a Pharmacology to Payer Framework to Support Product Development

Cost-utility Analysis of Antiviral Use Under Pandemic Influenza Using a Novel Approach—Linking Pharmacology, Epidemiology and Heath Economics

Surveying the Lay of the Land for Modeling & Simulation for Global Regulatory Submissions

Clinical Pharmacology Tools and Evaluations to Facilitate Comprehensive Dose Finding in Oncology: A Continuous Risk-Benefit Approach

Drug Asset Evaluation: Increasing “Probability of Success” of a Deal

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