Publication

Bioequivalence Analysis of Ondansetron Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Two-Period Crossover Phase I Study

Explore how ondansetron formulations are bioequivalent under fasting and fed conditions, confirmed using Phoenix WinNonlin.

CertaraOctober 29, 2024

Blog

Why you need an integrated development plan

Learn about the Integrated Development Plan for successful drug development & its relation to the…

CertaraOctober 17, 2024

Fact Sheet

Academic Centers of Excellence for Model-informed Drug Development (MIDD)

CertaraOctober 16, 2024

Publication

Medicines in pregnancy: A clinical pharmacology extrapolation framework to address knowledge gaps

CertaraOctober 16, 2024

Conference

16th Annual World ADC London 2026

CertaraOctober 11, 2024

Blog

Why cancer drug programs need human mass balance studies

Historically, drug programs for oncology and other rapidly fatal diseases didn’t include mass balance studies…

CertaraSeptember 23, 2024

Publication

A Pharmacokinetic/Toxicodynamic Model of Cisplatin Nephrotoxicity Using the Kidney Injury Molecule‑1 Biomarker

Discover how PK‑TD modelling shows palonosetron reduces platinum exposure and KIM‑1 elevations versus other antiemetics…

CertaraSeptember 20, 2024

Publication

Intravenous Versus Intraosseous Use of Tranexamic Acid in Patients With Traumatic Brain Injury

See how IV and intraosseous TXA show similar total exposure in prehospital TBI care, analysed…

CertaraSeptember 2, 2024

Publication

Utilizing an acute hyperthermia-induced seizure test and pharmacokinetic studies to establish optimal dosing regimens in a mouse model of Dravet syndrome

Learn how triple‑drug combinations increase clobazam metabolite exposure and improve seizure control, modelled using Phoenix…

CertaraAugust 30, 2024

Publication

In Vivo Activity of Intestinal P-Glycoprotein and Hepatic Organic Anion Transporters Polypeptide in Pregnancy and Postpartum

Find out how rosuvastatin exposure increases during pregnancy due to reduced OATP activity, while P‑gp…

CertaraAugust 27, 2024

Clinical Pharmacology

Bioequivalence Analysis of Ondansetron Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Two-Period Crossover Phase I Study

Why you need an integrated development plan

Academic Centers of Excellence for Model-informed Drug Development (MIDD)

Medicines in pregnancy: A clinical pharmacology extrapolation framework to address knowledge gaps

16th Annual World ADC London 2026

Why cancer drug programs need human mass balance studies

A Pharmacokinetic/Toxicodynamic Model of Cisplatin Nephrotoxicity Using the Kidney Injury Molecule‑1 Biomarker

Intravenous Versus Intraosseous Use of Tranexamic Acid in Patients With Traumatic Brain Injury

Utilizing an acute hyperthermia-induced seizure test and pharmacokinetic studies to establish optimal dosing regimens in a mouse model of Dravet syndrome

In Vivo Activity of Intestinal P-Glycoprotein and Hepatic Organic Anion Transporters Polypeptide in Pregnancy and Postpartum

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