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R Speaks NLME (RsNLME)

Open source flexibility for population PK/PD modeling

Advanced population PK/PD modeling made simple

With PopPK analysis now a standard requirement for regulatory submissions and expected by the FDA, scientists need flexible tools to streamline population PK/PD modeling. By integrating the Certara NLME engine directly into the R command line, RsNLME delivers unmatched flexibility and efficiency for pharmacometric workflows.

Whether you’re a novice or an advanced user, RsNLME equips you with the software and resources to elevate your modeling capabilities, including educational guides, tutorials, and demonstration vignettes.

Enables flexible and seamless model workflow

Allows users to define models without in-depth knowledge of underlying code

Reduces time spent performing analyses

Simplifying pharmacometric modeling with seamless R integration

RsNLME simplifies population PK/PD modeling by offering seamless integration with open-source R tools. It supports both graphical user interfaces and command-line workflows, reducing the time spent on model translation and enabling real-time configurable model output reports.

Fully compatible with Phoenix WinNonlin™ and Phoenix NLME™ models
Provides R tidyverse-based syntax for streamlined model manipulation
Includes user-friendly educational materials and training resources

Why Certara

Certara empowers scientists with innovative tools and expertise to accelerate drug development and improve decision-making.

  • Certara, a leader in biosimulation and modeling solutions, has made pharmacometrics a cornerstone of its expertise.
  • Our modeling software is trusted by industry leaders and recognized by regulatory authorities as a reliable solution.
  • Building on our proven AI capabilities, we continue to enhance our solutions across the drug development lifecycle, making them faster and more effective.

Pharmacokinetic and pharmacodynamic data analysis

Certara is proud to offer a golden opportunity for learners and experts in pharmacokinetics & pharmacodynamics! Prof Johan Gabrielsson’s standard book will be available FREE of charge!

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Get a 30-day free trial

Experience how RsNLME can revolutionize your pharmacometric workflows with a free one-month trial. Explore its powerful features and seamless integration with Certara’s NLME engine, designed to streamline your modeling process.

Streamline population PK/PD modeling with open-source flexibility
Access comprehensive educational resources and tutorials
Enhance efficiency with real-time configurable reports