The Antibody-Drug Conjugate (ADC) Model Pack offers unparalleled insights into ADC pharmacology. This pre-built model pack is used with Certara IQ™, and each model includes mechanism of action diagrams, pharmacology diagrams, and a comprehensive set of parameters derived from extensive literature research. This robust toolkit is ideal for researchers aiming to optimize ADC design and predict therapeutic outcomes.
ADC Model Pack
Pre-built library of validated QSP models for ADCs with and without avidity
QSP Model Pack for Antibody-Drug Conjugates (ADC)
Includes 42 models for monospecific and bispecific ADCs
Features avidity effects and multi-compartment pharmacokinetics
Supports in vitro and in vivo simulations
Model diagrams and parameters
Each model in the ADC Model Pack includes a mechanism of action diagram and a pharmacology diagram with model parameters and their nominal values. Each model in Certara IQ has a unique set of parameters, based on the model pharmacology and number of compartments. In the app, each parameter contains a default value based on expansive literature searches and references. Below is a representative model diagram.
Created in Biorender
Differentiate Your ADC Development with Mechanistic QSP Modeling
As ADC programs grow more complex—incorporating bispecifics, novel payloads, and advanced formats—mechanistic QSP modeling becomes essential. In this video, Piet van der Graaf highlights how biosimulation supports translational pharmacology, dose selection, and strategic differentiation in an increasingly competitive ADC field.
Explore other Certara IQ QSP model packs
In addition to the ADC model pack, Certara IQ offers several libraries of monospecific and bispecific, single-compartment and multicompartment models covering common pharmacologies.
Related resources
View allDownload the ADC model pack
Discover how Certara’s Antibody-Drug Conjugate (ADC) Model Pack in Certara IQ can transform your ADC research.
Gain insights into ADC pharmacology with 42 detailed models
Visualize mechanisms of action and pharmacokinetics
Customize parameters to fit your research needs
Certara IQ Support
Have questions about how model pack libraries accelerate modeling in Certara IQ?
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