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Conference: EACPT 2025 CONGRESS

Date: June 28 - July 1, 2025

Location: Helsinki, Finland

Booth: 3

Hear about the latest innovations in drug interaction science

Catch up with the foremost experts in drug interaction science at the 2025 EACPT Congress. Certara offers a mix of software and services to optimize DDI knowledge throughout drug development, including the industry’s largest scientist-curated database for assessing drug interactions and safety – the Drug Interaction Database (DIDB®)

You’ll have the opportunity to meet Isabelle Ragueneau-Majlessi, MD, MS, a Distinguished Scientist at Certara, co-founder of the DIDB and core team member of the Center of Excellence in Drug Interaction Science.

Isabelle Ragueneau-Majlessi
Isabelle Ragueneau-Majlessi, MD, MS

Distinguished Scientist, Drug Interaction Solutions

Get an exclusive preview of DIDB’s ConMed Navigator

Built on regulatory agency-recommended classifications and powered by DIDB data, ConMed Navigator is scheduled to launch in Fall 2025. Sign up for a sneak preview exclusive to EACPT 2025 attendees and learn about how CoMed Navigator helps scientists to quickly identify concomitant medications and more:

    • Search a comprehensive list of drug characteristics, anchored to marker studies, to assess potential DDI risk and inform clinical development strategies for your NME
    • Improve drug labeling and provide clinical context with specific examples of concomitant medications related to your target patient population

Complete this form to schedule a DIDB product demo at EACPT

Comprehensive and Scalable QSP Solutions

Certara’s Quantitative Systems Pharmacology (QSP) solutions combine scientific rigor with state-of-the-art QSP software to enhance decision-making at every stage of drug development. Our QSP platforms are highly scalable, enabling tailored model development to address specific therapeutic areas such as immunology, oncology, and rare diseases. By incorporating mechanistic insights and integrating diverse data sources, our solutions provide a holistic understanding of drug behavior and patient response.

With over 65 expert scientists and a track record of success across 250+ global clients, Certara delivers unparalleled expertise in QSP modeling and simulation. Whether assessing feasibility early in discovery, optimizing dose selection, predicting clinical outcomes, or de-risking R&D investments, our comprehensive approach empowers you to make smarter, faster decisions.

Meet our world-renowned QSP expert, Dr. Piet van der Graaf to find out how QSP modeling is transforming drug development from end-to-end.

Piet van der Graaf, PharmD, PhD

Senior Vice President and Head of Quantitative Systems Pharmacology

Where to hear Certara insights and Expertise

Sunday, June 29, 2025, 10:30-11 am
QSP Modeling: Speeding dose escalation trials in immuno-oncology

Session B1: Preclinical data informing clinical pharmacology

Session Chairs: Mikko Koskinen (Orion Corporation) and Piet van der Graaf (Certara)

Presenter: Piet van der Graaf, Professor of Systems Pharmacology, University of Leiden, The Netherlands
Senior VP and Head of QSP, Certara

Monday, June 30, 2025, 11:30 am - 12:00pm
Model-informed drug development for rare diseases

Session B5: Addressing unmet needs

Session Chairs: Timo Myöhänen (University of Helsinki) and Caridad Pontes (Universitat Autónoma de Barcelona)

Presenter: Piet van der Graaf, Professor of Systems Pharmacology, University of Leiden, The Netherlands
Senior VP and Head of QSP, Certara

Poster presentation

Clinical Pharmacology Considerations applied to Radioligand therapies (RLTs)

Authors: Diane-Charlotte Imbs, Amandine Manon, Dennis Heller, William Copalu

As radioligand therapies (RLTs) gain traction in oncology, regulatory guidance on clinical pharmacology remains limited. This poster outlines practical, experience-based recommendations to define a robust clinical pharmacology strategy for RLTs. Drawing on FDA/EMA interactions, we propose integrating ADME characterization, DDI assessments, QTc risk evaluation, special population analyses, immunogenicity considerations, and dose optimization, ideally within First-in-Human (FIH) studies. These insights aim to support sponsors navigating evolving expectations and preparing for later-phase development.

Get an exclusive preview of DIDB’s ConMed Navigator

Sign up for a sneak preview exclusive to EACPT 2025 attendees and learn about how CoMed Navigator helps scientists to quickly identify concomitant medications and more