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QSP Knowledge Base

World-renowned thought leadership

A collection of resources to deepen the understanding of QSP impact

Quantitative Systems Pharmacology (QSP) is an emerging discipline that has already demonstrated its vast potential to improve biopharmaceutical R&D and inform decision-making across drug development. This mechanistic approach combines computational modeling and experimental data to examine the relationships between a drug, the biological system, and the disease process. With the ability to leverage big data (biological and pharmacological), it enables the understanding of disease pathophysiology and the identification and testing of therapeutic strategies in virtual trials with virtual patients. Certara’s QSP Center of Excellence has been actively advancing the field of QSP in drug discovery and development by providing QSP consulting services and QSP software tools.

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Our QSP offerings

Choose Certara's Quantitative Systems Pharmacology (QSP) consulting services to enhance drug development with computational modeling and experimental data.

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Certara's QSP modeling software enables modelers and scientists to predict drug efficacy and safety utilizing mathematical modeling and virtual trials.

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QSP modeling software for non-modelers. Assess feasibility earlier for therapeutics across various modalities and disease areas.

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Certara’s QSP modeling platform for immuno-oncology predicts optimal combinations, dose regimens, and biomarkers in virtual patients, for IO therapies. 

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Certara’s Inflammatory Bowel Disease (IBD) QSP Platform Model is based on a mechanistic multi-state mathematical model to predict disease activity scores.

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Certara’s Immunogenicity (IG) Simulator is a QSP immunogenicity prediction tool that predicts immunogenicity incidence and its impact on PK/PD.

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Certara’s Vaccine Simulator uses Quantitative Systems Pharmacology (QSP) to determine optimal vaccine dosing strategies for patients.

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Certara’s QSP models for neuroscience drug discovery offer mechanism-based models for Alzheimer’s, Parkinson’s, psychotic disorders, and more.

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Connect with the QSP experts

Connect with Certara to discuss how QSP services can accelerate your drug development program. Our team of experts is ready to provide tailored solutions for your specific needs.

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