Delays are ubiquitous in pharmacokinetics (PK) and pharmacodynamics (PD) studies. Transit compartment models, described by systems of ordinary differential equations, have been widely used to describe delayed outcomes in PK and PD studies. The obvious disadvantage for this type of model is it requires manually finding proper values for the number of compartments. In addition, […]Read More
Author: Shuhua Hu
Dr. Shuhua Hu is a senior research scientist in the scientific group at Certara. Before she joined Certara, she had worked at North Carolina State University for ten years with a research focus on mathematical modeling, simulation, estimation, optimal control, and uncertainty propagation and quantification in the area of biomedicine and engineering. She has published over thirty peer-review journal publications and a book “Modeling and Inverse Problems in the Presence of Uncertainty”.
Subscribe to Email Updates
- EMA Policy 0070 Compliance Tips from James Bond
- Modeling Delayed Outcomes in PK/PD Studies Using DDEs
- The Model-Informed Precision Dosing Revolution Is Coming
- Leveraging PBPK Modeling and Simulation for Neonatal and Infant Drug Development
- Accessing Grid Computing from Your Desktop for NLME
- Prediction of Liver Volume; One Size Doesn’t Fit All!
- Streamline Your Approach to EMA Policy 0070
- How Model-Informed Drug Development Will Increase R&D Productivity
- Transforming Drug Product Development the PBPK Way! -A Breakthrough Approach
- How MBMA Can Help You Make Smarter Drug Development Decisions