Modeling Approaches for Determination of Pharmacokinetics/Pharmacodynamics

The BioPharm International article, Modeling Approaches for Determination of Pharmacokinetics/Pharmacodynamics by Cynthia A. Challener, highlights the pivotal role of PK/PD modeling in modern drug development. Innovators such as Certara’s Piet van der Graaf and Hannah M. Jones provide insights into how advanced biosimulation tools like QSP and PBPK modeling are reshaping biologics development through data-driven, predictive approaches. These methods enhance precision, optimize dosing, and reduce reliance on traditional trial-and-error practices, positioning PK/PD modeling as a cornerstone of efficient and ethical drug development.