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ADC Model Pack

Pre-built library of validated QSP models for ADCs with and without avidity

QSP model pack for antibody-drug conjugates

The Antibody-Drug Conjugate (ADC) Model Pack offers unparalleled insights into ADC pharmacology. This pre-built model pack is used with Assess™, and each model includes mechanism of action diagrams, pharmacology diagrams, and a comprehensive set of parameters derived from extensive literature research. This robust toolkit is ideal for researchers aiming to optimize ADC design and predict therapeutic outcomes.

Includes 42 models for monospecific and bispecific ADCs 

Features avidity effects and multi-compartment pharmacokinetics

Supports in vitro and in vivo simulations 

Model diagrams and parameters

Each model in the ADC Model Pack includes a mechanism of action diagram and a pharmacology diagram with model parameters and their nominal values. Each model in Assess™ has a unique set of parameters, based on the model pharmacology and number of compartments. In the app, each parameter contains a default value based on expansive literature searches and references. Below is a representative model diagram.

QSP model diagram for antibody drug conjugates (ADCs)

Created in Biorender

Explore other Assess™ QSP model packs

In addition to the ADC model pack, Assess™ offers several libraries of monospecific and bispecific, single-compartment and multicompartment models covering common pharmacologies.

Download the ADC model pack

Discover how Certara’s Antibody-Drug Conjugate (ADC) Model Pack in AssessTM can transform your ADC research.

Gain insights into ADC pharmacology with 42 detailed models
Visualize mechanisms of action and pharmacokinetics
Customize parameters to fit your research needs

On-demand support

Have any questions about AssessTM model packs? We have software engineers ready to chat!

Email us at [email protected]

Documentation

Visit our AssessTM documentation portal for product documentation as well as video case studies.

View Documentation Portal