IQ WG Evaluation of PBPK Models for Organ-Impaired Populations
• The predictive performance of physiologically based pharmacokinetic(s) (PBPK) models for PK in renal impairment…
CertaraMarch 10, 2021
Simcyp™ PBPK Simulator
Streamlines drug development by using PBPK modeling to predict drug behavior in virtual populations, optimize…
CertaraJanuary 22, 2021
How PBPK Modeling Can Replace Drug-Drug Interaction Studies
Patients often take more than one drug at a time, especially elderly patients and those…
CertaraNovember 12, 2020
Galderma Achieves FDA Approval of AKLIEF® (trifarotene)
In October 2019, Galderma announced that the U.S. FDA approved AKLIEF® (trifarotene) Cream, 0.005% for the…
CertaraNovember 9, 2020
PBPK modeling supports approval of breakthrough cancer drug
Pharmacyclics’ (now AbbVie) Imbruvica (ibrutinib) is an anticancer drug targeting B-cell malignancies. Leveraging the US…
CertaraOctober 23, 2020
