INVESTIGATING THE IMPACT OF ENZYME CORRELATIONS ON INTER-INDIVIDUAL VARIABILITY IN PHARMACOKINETICS AND DRUG-DRUG INTERACTIONS Poster INVESTIGATING THE IMPACT OF ENZYME CORRELATIONS ON INTER-INDIVIDUAL VARIABILITY IN PHARMACOKINETICS AND DRUG-DRUG INTERACTIONS CertaraSeptember 4, 2019
Biokinetic and PBPK modelling to support the rotenone and strobilurin read across case studies (CS4) Poster Biokinetic and PBPK modelling to support the rotenone and strobilurin read across case studies (CS4) CertaraSeptember 4, 2019
Biokinetic and PBPK Modelling to Support Read-Across Assessment of Repeat Dose and Developmental and Reproductive Toxicity of Valproic Acid Analogues Poster Biokinetic and PBPK Modelling to Support Read-Across Assessment of Repeat Dose and Developmental and Reproductive Toxicity of Valproic Acid Analogues CertaraSeptember 4, 2019
Physiologically Based Pharmacokinetic/Pharmacodynamic model of gastrointestinal toxicity induced by 5-fluorouracil in mouse and translation to human Poster Physiologically Based Pharmacokinetic/Pharmacodynamic model of gastrointestinal toxicity induced by 5-fluorouracil in mouse and translation to human CertaraSeptember 4, 2019
Use of a Physiologically based Pharmacokinetic – Pharmacodynamic Model to Account for Adjustments to dosing of S-warfarin in Different Populations Poster Use of a Physiologically based Pharmacokinetic – Pharmacodynamic Model to Account for Adjustments to dosing of S-warfarin in Different Populations CertaraSeptember 3, 2019
Quantitative description of the physiological changes in diseased skin and their incorporation into Physiologically Based Pharmacokinetic Models. Poster Quantitative description of the physiological changes in diseased skin and their incorporation into Physiologically Based Pharmacokinetic Models. CertaraSeptember 3, 2019
Predicting Diffusion in the Dermis: a Physiologically Based, Bottom-up Approach Poster Predicting Diffusion in the Dermis: a Physiologically Based, Bottom-up Approach CertaraSeptember 3, 2019
Modeling in vitro skin permeation experiments to mechanistically understand in vivo dermal absorption: Application of in vitro-in vivo extrapolation (IVIVE) and physiological based pharmacokinetic (PBPK) modeling using testosterone as model drug Poster Modeling in vitro skin permeation experiments to mechanistically understand in vivo dermal absorption: Application of in vitro-in vivo extrapolation (IVIVE) and physiological based pharmacokinetic (PBPK) modeling using testosterone as model drug CertaraSeptember 3, 2019
Assessing the Bioequivalence of Tacrolimus Amorphous Formulations with Varying Degrees of Crystallinity using Mechanistic Dissolution Models in a Population Physiologically-based Pharmacokinetic (PBPK) Modelling Framework Poster Assessing the Bioequivalence of Tacrolimus Amorphous Formulations with Varying Degrees of Crystallinity using Mechanistic Dissolution Models in a Population Physiologically-based Pharmacokinetic (PBPK) Modelling Framework CertaraSeptember 3, 2019
Application of Feto-Placental-Maternal Physiologically-based Pharmacokinetic Model to Predict Tenofovir Concentration during Pregnancy Poster Application of Feto-Placental-Maternal Physiologically-based Pharmacokinetic Model to Predict Tenofovir Concentration during Pregnancy CertaraSeptember 3, 2019
