Enhancing Pharmacokinetics Workflows at Charles River
PreclinicalPhoenix™ Integral Data Repository Charles River, a global leader in drug development, sought to improve…
CertaraNovember 13, 2024
PBPK Modeling to Support Bioequivalence & Generic Product Approvals
Physiologically-based pharmacokinetic modeling can be used to support bioequivalence (BE) assessment of complex and locally…
CertaraNovember 12, 2024
Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody
The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…
CertaraNovember 4, 2024
On-ramps to popPK: Building Better Models with GUI, Code, or Both
A critical component of popPK studies is popPK modeling, where mathematical models are developed to…
CertaraOctober 18, 2024
Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator
The article "Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system…
CertaraAugust 26, 2024
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)
The article “Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL)…
CertaraAugust 26, 2024
A guide to developing population files for physiologically-based pharmacokinetic modeling in the Simcyp Simulator
This collaborative effort by Certara and the Centre for Applied Pharmacokinetic Research (CAPKR) at The…
CertaraJuly 24, 2024
