Publication

Population Pharmacokinetics and Pharmacogenetics Analyses of Dasatinib in Chinese Patients with Chronic Myeloid Leukemia

Explore how age increases dasatinib exposure; PopPK modelling supports lower dosing in elderly Chinese CML…

CertaraSeptember 19, 2023

Case Study

How A Biotech Startup Company Increased Flexibility and Efficiency by Switching to Phoenix Cloud

Discover how a biotech startup enhanced flexibility and efficiency by adopting Phoenix Hosted, streamlining workflows…

CertaraSeptember 8, 2023

Publication

Population pharmacokinetics and pharmacogenetics analyses of imatinib in Chinese patients with chronic myeloid leukemia in a real-world situation

Discover how hemoglobin and eGFR drive imatinib PK variability; PopPK modelling supports caution in renal…

CertaraAugust 25, 2023

Publication

Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study

See how active uptake occurs at both BBB and BCSFB with no sex differences, analysed…

CertaraAugust 23, 2023

Publication

An HPLC-MS/MS method for determination of sulbactam in human plasma and its pharmacokinetic application in critically ill patients with augmented renal clearance

Learn how ARC patients show lower sulbactam exposure and higher clearance, supporting dose increases, analysed…

CertaraAugust 1, 2023

Publication

Evaluation of ceftriaxone pharmacokinetics in hospitalized Egyptian pediatric patients

Find out how renal function and hypoalbuminemia alter ceftriaxone PK; current dosing remains appropriate, analysed…

CertaraJuly 24, 2023

Publication

Pharmacokinetic and Bioequivalence Evaluation of Single-Tablet and Separate-Tablet Regimens for Ainuovirine, Lamivudine, and Tenofovir Disoproxil Fumarate in Chinese Healthy Subjects

Explore how single‑tablet regimen matches exposure of separate tablets with comparable safety, analysed using Phoenix…

CertaraJuly 20, 2023

Publication

Population pharmacokinetic analysis of transdermal granisetron in healthy Chinese and Caucasian volunteers

Discover how no demographic covariates significantly affect granisetron patch PK; no dose adjustment needed, modelled…

CertaraJune 26, 2023

Publication

Safety and pharmacokinetic comparison between fenofibric acid 135 mg capsule and 110 mg enteric-coated tablet in healthy volunteers

See how enteric‑coated tablet shows higher bioavailability and delayed peak vs capsule, analysed using Phoenix…

CertaraJune 16, 2023

Publication

Liquid Chromatography-Tandem Mass Spectrometry Method for Detection and Quantification of Meloxicam and 5′-Carboxymeloxicam in Oral Fluid Samples

Learn how oral‑fluid LC‑MS/MS enables minimally invasive meloxicam PK/PD assessment, analysed using Phoenix WinNonlin.

CertaraJune 15, 2023

Certara Products – Phoenix

Population Pharmacokinetics and Pharmacogenetics Analyses of Dasatinib in Chinese Patients with Chronic Myeloid Leukemia

How A Biotech Startup Company Increased Flexibility and Efficiency by Switching to Phoenix Cloud

Population pharmacokinetics and pharmacogenetics analyses of imatinib in Chinese patients with chronic myeloid leukemia in a real-world situation

Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study

An HPLC-MS/MS method for determination of sulbactam in human plasma and its pharmacokinetic application in critically ill patients with augmented renal clearance

Evaluation of ceftriaxone pharmacokinetics in hospitalized Egyptian pediatric patients

Pharmacokinetic and Bioequivalence Evaluation of Single-Tablet and Separate-Tablet Regimens for Ainuovirine, Lamivudine, and Tenofovir Disoproxil Fumarate in Chinese Healthy Subjects

Population pharmacokinetic analysis of transdermal granisetron in healthy Chinese and Caucasian volunteers

Safety and pharmacokinetic comparison between fenofibric acid 135 mg capsule and 110 mg enteric-coated tablet in healthy volunteers

Liquid Chromatography-Tandem Mass Spectrometry Method for Detection and Quantification of Meloxicam and 5′-Carboxymeloxicam in Oral Fluid Samples

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