Publication

Population pharmacokinetics of rotigotine extended‑release microspheres for intramuscular injection in early‑stage Parkinson’s disease

Discover how body weight meaningfully affects rotigotine ER exposure; race has minimal impact, modelled using…

CertaraJanuary 17, 2024

Publication

Effect of High-Fat Meal on the Pharmacokinetics and Safety of Valsartan/Amlodipine Fixed Dose Combination Tablets in Healthy Subjects

See how high‑fat meals reduce valsartan exposure by over 50% while amlodipine PK is unaffected,…

CertaraJanuary 11, 2024

Publication

Population pharmacokinetic modeling of ilaprazole in healthy subjects and patients with duodenal ulcer in China

Learn how the first Chinese PopPK model shows weight, sex, and ulcer status influence ilaprazole…

CertaraJanuary 10, 2024

Publication

Simultaneous determination of amphotericin B, tobramycin and vancomycin in rabbit ocular biofluids and tissues by LC-MS/MS: An antimicrobial therapy for keratitis and its PK-PD application

Find out how triple‑drug ocular PK‑PD modelling identifies optimal dosing frequency for keratitis therapy using…

CertaraDecember 31, 2023

Publication

Concurrent determination of anti-microbial and anti-inflammatory drugs in lachrymal fluid and tissue by LC-MS/MS: A potential treatment for microbial keratitis and its PK-PD evaluation

Explore how validated LC‑MS/MS and PK‑PD simulation support pathogen‑specific dosing for microbial keratitis using Phoenix…

CertaraDecember 13, 2023

Publication

Bioequivalence Study of Capsules versus Film Tablets Containing Rivaroxaban in Healthy Caucasian Subjects under Fasting and Fed Conditions

Discover how capsule and tablet rivaroxaban formulations are bioequivalent with comparable safety, analysed using Phoenix…

CertaraNovember 23, 2023

Publication

Unveiling the Influence of a High-Fat Meal on the Pharmacokinetics of Oral Globalagliatin, A Glucokinase Activator, in Healthy Chinese Volunteers

See how high‑fat meals increase globalagliatin exposure by 25–35%, supporting food‑related dosing guidance using Phoenix…

CertaraNovember 20, 2023

Publication

Population pharmacokinetics of rivaroxaban in Chinese deep vein thrombosis patients and the exposure simulation for dosing recommendation.

Learn how eGFR strongly influences rivaroxaban clearance; PopPK modelling supports renal‑based dose reductions using Phoenix…

CertaraNovember 11, 2023

On-Demand Webinar

Compliance in the Cloud: What you need to know about computer system validation when moving your application to the cloud

Learn key insights on computer system validation and compliance when moving applications to the cloud.…

CertaraOctober 27, 2023

Publication

Association Study of Esomeprazole Pharmacokinetics and CYP2C19 Gene Polymorphisms

Find out how CYP2C19 polymorphisms significantly affect esomeprazole exposure and half‑life, analysed using Phoenix WinNonlin.

CertaraSeptember 29, 2023

Certara Products – Phoenix

Population pharmacokinetics of rotigotine extended‑release microspheres for intramuscular injection in early‑stage Parkinson’s disease

Effect of High-Fat Meal on the Pharmacokinetics and Safety of Valsartan/Amlodipine Fixed Dose Combination Tablets in Healthy Subjects

Population pharmacokinetic modeling of ilaprazole in healthy subjects and patients with duodenal ulcer in China

Simultaneous determination of amphotericin B, tobramycin and vancomycin in rabbit ocular biofluids and tissues by LC-MS/MS: An antimicrobial therapy for keratitis and its PK-PD application

Concurrent determination of anti-microbial and anti-inflammatory drugs in lachrymal fluid and tissue by LC-MS/MS: A potential treatment for microbial keratitis and its PK-PD evaluation

Bioequivalence Study of Capsules versus Film Tablets Containing Rivaroxaban in Healthy Caucasian Subjects under Fasting and Fed Conditions

Unveiling the Influence of a High-Fat Meal on the Pharmacokinetics of Oral Globalagliatin, A Glucokinase Activator, in Healthy Chinese Volunteers

Population pharmacokinetics of rivaroxaban in Chinese deep vein thrombosis patients and the exposure simulation for dosing recommendation.

Compliance in the Cloud: What you need to know about computer system validation when moving your application to the cloud

Association Study of Esomeprazole Pharmacokinetics and CYP2C19 Gene Polymorphisms

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