Using a pharmacology to payer framework to support product development Blog Using a pharmacology to payer framework to support product development Modeling and simulation (M&S) of complex systems has primarily advanced vertically in differing scientific domains…CertaraMarch 16, 2018
Cost-utility Analysis of Antiviral Use Under Pandemic Influenza Using a Novel Approach—Linking Pharmacology, Epidemiology and Heath Economics Publication Cost-utility Analysis of Antiviral Use Under Pandemic Influenza Using a Novel Approach—Linking Pharmacology, Epidemiology and Heath Economics CertaraMarch 1, 2018
Treatment of Adult Chronic Indeterminate Chagas Disease with Benznidazole and Three E1224 Dosing Regimens: A Proof-of-concept, Randomised, Placebo-controlled Trial Publication Treatment of Adult Chronic Indeterminate Chagas Disease with Benznidazole and Three E1224 Dosing Regimens: A Proof-of-concept, Randomised, Placebo-controlled Trial CertaraJanuary 15, 2018
Model-informed Drug Development for Malaria Therapeutics Publication Model-informed Drug Development for Malaria Therapeutics CertaraJanuary 6, 2018
Interdisciplinary Pharmacometrics Linking Oseltamivir Pharmacology, Influenza Epidemiology and Health Economics to Inform Antiviral Use in Pandemics Publication Interdisciplinary Pharmacometrics Linking Oseltamivir Pharmacology, Influenza Epidemiology and Health Economics to Inform Antiviral Use in Pandemics CertaraJuly 1, 2017
Isoniazid Clearance is Impaired Among Human Immunodeficiency Virus/Tuberculosis Patients with High Levels of Immune Activation Publication Isoniazid Clearance is Impaired Among Human Immunodeficiency Virus/Tuberculosis Patients with High Levels of Immune Activation CertaraApril 1, 2017
A Pharmacokinetic/Viral Kinetic Model to Evaluate Treatment of Chronic HCV Infection with a Non-nucleoside Polymerase Inhibitor Publication A Pharmacokinetic/Viral Kinetic Model to Evaluate Treatment of Chronic HCV Infection with a Non-nucleoside Polymerase Inhibitor CertaraJanuary 10, 2017
Limitations of MIC as Sole Metric of Pharmacodynamic Response Across the Range of Antimicrobial Susceptibilities within a Single Bacterial Species Publication Limitations of MIC as Sole Metric of Pharmacodynamic Response Across the Range of Antimicrobial Susceptibilities within a Single Bacterial Species The minimum inhibitory concentration (MIC) of an antimicrobial drug for a bacterial pathogen is used…CertaraDecember 1, 2016
Pharmacokinetics of Oral Terbinafine in Adult Horses Publication Pharmacokinetics of Oral Terbinafine in Adult Horses The primary study objective was to compare the pharmacokinetics of p.o. terbinafine alone to p.o.…CertaraNovember 24, 2016
Vaccination Mitigates the Impact of PRRSv Infection on the Pharmacokinetics of Ceftiofur Crystalline-free Acid in Pigs Publication Vaccination Mitigates the Impact of PRRSv Infection on the Pharmacokinetics of Ceftiofur Crystalline-free Acid in Pigs The pharmacokinetics of intramuscularly administered ceftiofur crystalline-free acid (CCFA) were determined in pigs that were…CertaraNovember 24, 2016