Clinical Pharmacology & Model-Informed Drug Development Insights for Targeted Radiation Therapies
Targeted radiation therapies (TRT) deliver cytotoxic radiation selectively to tumors. In recent years, oncology drug…
CertaraMay 22, 2024
Reflections on the new FDA clinical pharmacology guidance for antibody-drug conjugates
In recent years, oncology drug developers have invested in antibody-drug conjugates (ADCs). These targeted therapies…
CertaraMay 10, 2024
Dose optimization considerations for targeted radiation therapies
The acquisitions of targeted radiation therapy companies (TRT) Point Biopharma by Eli Lilly and RayzeBio…
CertaraFebruary 16, 2024
Modeling and simulation in pediatric drug development
Published: December 21, 2023 This is the article written in German, published on pharmind. Children's…
CertaraDecember 21, 2023
Translational Pharmacology Consulting Supports Combination Therapy for Treating Pulmonary Mycobacterium Avium Complex Disease
RedHill Biopharma Ltd., a specialty biopharmaceutical company, developed RHB-204, a treatment for MAC, and needed…
CertaraMay 9, 2023
Tumor Dynamic Model-Based Decision Support for Phase Ib/II Combination Studies: A Retrospective Assessment Based on Resampling of the Phase III Study IMpower150
Explore how tumor growth inhibition modeling can support go/no-go decisions in early Phase Ib/II oncology…
CertaraMarch 24, 2023
