Bispecifics Archives

Poster

Abstract Trimer formation is key to the pharmacology of the bispecific ATG-101 but is difficult…

CertaraSeptember 16, 2024

Poster

Insights from a Mechanistic PKPD Model on the Implications for Switching from Infusion to Subcutaneous…

CertaraSeptember 16, 2024

Poster

Abstract DuoBody®-PD-L1x4-1BB (GEN1046) is an investigational, first-in-class, bispecific antibody designed to elicit an antitumor immune…

CertaraSeptember 9, 2024

Poster

Abstract Bispecific drugs have great potential to improve tissue selectivity through avid binding interactions but…

CertaraSeptember 9, 2024

Poster

Abstract Objectives: The presence of target receptors in non-target tissues can reduce the therapeutic window…

CertaraSeptember 9, 2024

Case Study

Strategic mechanistic modeling solutions help an immunoncology biotech accelerate their clinical development of novel therapeutics.

CertaraAugust 16, 2024

Bispecifics