Accounting for CYP2C19 mechanism based inhibition and CYP1A2 induction in a PBPK model for omeprazole Poster
Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir® Tablet Absorption in Humans Under Fasted and Fed State Conditions Poster
Use of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model to guide dose adjustments to S-warfarin in different populations Poster
Quantitative Systems Toxicology Approach Integrates Simcyp PBPK and Core Hepatocyte Metabolism: a Case Study with Valproic Acid Poster
The Certara Quantitative Systems Toxicology & Safety (QSTS) Pharma Consortium: Overview and Invitation to Join Poster
Development of a PBPK model for the prediction of Amiodarone pharmacokinetics in fed and fasted state using ADAM model Poster
Predictive Performance of Caffeine Preterm PBPK Model and Effect of Time-Varying Physiology on Predictions Poster
Dosing corrected for species differences in toxicokinetics using PBPK modelling predicts equivalent reactive metabolite burden following acetaminophen overdose Poster
Development of a Permeability-Limited Cardiac Physiologically-Based Pharmacokinetic Model for Predicting Cardiac Exposure Poster
