Model-informed Drug Development
Incorporating population variability into mechanistic prediction of PK and modeling PK/PD
July 6–10 in Cambridge, MA
Full workshops offer an in-depth insight into specific areas of modeling such as:
- Gut first-pass metabolism
- Oral drug absorption incorporating food effects and the impact of dosage form
- Effect of transporters and enterohepatic recirculation on kinetics and DDIs
- Drug distribution to different organs
- Population variability in drug concentration-time profiles
- Variation in kinetics in specific populations (pediatrics, ethnic groups, various disease populations)
- Modeling of therapeutic proteins
- Pharmacodynamic effects of different compounds
- Time-course of drug in plasma that fits observed clinical data (achieved by combining fitting techniques with IVIVE, PBPK and drug-specific in vitro data)
How do I register?
Online booking for Simcyp events is handled through the Simcyp Members’ Area. Your saved profile is automatically captured on the booking form so there is no need to re-enter your contact details. Click here to link to the booking forms—you will be prompted for your Simcyp Members’ Area user name (email address) and password. If you have forgotten your log-in credentials please follow the instructions on-screen.
If you have not yet registered for the Members’ Area please sign up now.
The Society of Toxicology may have additional funding available for SOT-member graduate student (STEP) and postdoctoral (NEXT) trainees. Visit their respective websites for eligibility, application requirements and deadlines.