Quantification of drug metabolising enzymes and transporter proteins in the paediatric duodenum via LC-MS/MS proteomics using a QconCAT technique Publication Quantification of drug metabolising enzymes and transporter proteins in the paediatric duodenum via LC-MS/MS proteomics using a QconCAT technique Characterising the small intestine absorptive membrane is essential to enable prediction of the systemic exposure…CertaraAugust 29, 2023
Certara Launches v11.0 of SEND Explorer Announcement Certara Launches v11.0 of SEND Explorer Delivers advanced data analysis and visualization capabilities to support nonclinical scientists PRINCETON, N.J.— August 28,…CertaraAugust 28, 2023
Payers’ reaction to the IRA’s Medicare Part D Redesign Blog Payers’ reaction to the IRA’s Medicare Part D Redesign On August 16, 2022, President Biden signed the Inflation Reduction Act of 2022 (IRA) into…CertaraAugust 25, 2023
AMCP Poster – A survey-based analysis of the determinants of management in traditionally unmanaged categories of oncology and rare diseases Poster AMCP Poster – A survey-based analysis of the determinants of management in traditionally unmanaged categories of oncology and rare diseases CertaraAugust 25, 2023
Development and Verification of a Japanese Pediatric Physiologically Based Pharmacokinetic Model with Emphasis on Drugs Eliminated by Cytochrome P450 or Renal Excretion Publication Development and Verification of a Japanese Pediatric Physiologically Based Pharmacokinetic Model with Emphasis on Drugs Eliminated by Cytochrome P450 or Renal Excretion Physiologically based pharmacokinetic (PBPK) models are useful in bridging drug exposure in different ethnic groups,…CertaraAugust 21, 2023
Development and application of a PBPK modeling strategy to support antimalarial drug development Publication Development and application of a PBPK modeling strategy to support antimalarial drug development As part of a collaboration between Medicines for Malaria Venture (MMV), Certara UK and Monash…CertaraAugust 18, 2023
Stop if you don’t have an unambiguous drug effect for your new molecular entity! Blog Stop if you don’t have an unambiguous drug effect for your new molecular entity! As a pharmacologist, I’ve always been curious about how drugs work. A favorite time-killer while…CertaraAugust 18, 2023
Computational neurosciences and quantitative systems pharmacology: a powerful combination for supporting drug development in neurodegenerative diseases Publication Computational neurosciences and quantitative systems pharmacology: a powerful combination for supporting drug development in neurodegenerative diseases Successful clinical development of new therapeutic interventions is notoriously difficult, especially in neurodegenerative diseases, where…CertaraAugust 15, 2023
IRA impacts: First 10 drugs selected for the Drug Price Negotiation Program On-Demand Webinar IRA impacts: First 10 drugs selected for the Drug Price Negotiation Program The Inflation Reduction Act (enacted in August 2022) contains profound changes for the healthcare and…CertaraAugust 15, 2023