Access This Exclusive On-Demand Webinar and Overview
Learn how to navigate the complex pharmacokinetics (PK) of antibody-drug conjugates (ADCs). In this exclusive on-demand session, our experts share essential strategies for progressing from basic non-compartmental analysis (NCA) to advanced population PK (popPK) modeling.
Through real-world examples and case studies, you’ll gain actionable insights to guide data-driven decision making throughout ADC development.
Key Takeaways
- Understand the fundamentals of ADC structure and mechanisms of action
- Learn the differences between internalizing and non-internalizing ADCs
- Apply NCA techniques to extract meaningful PK data
- Know when and how to transition from NCA to more advanced popPK modeling
- Explore real-world modeling case studies, including:
- A three-analyte popPK model
- Pediatric dose optimization through modeling and simulation
- Discover strategies to align model complexity with available data and development goals
Presenters
Dr. Martin Beliveau – Vice President, Consulting, Certara
Dr. Eline van Maanen – Director, Consulting, Certara
Dr. Kang Lin – Senior Scientist, Avidity Biosciences
Watch now to explore practical modeling approaches that streamline ADC development and regulatory decision-making.
