Past Event
Date
June 11-14, 2023
Location
UK
ISSX
Presentations and Posters
Sunday, June 11, 2023 - 09:00 - 12:30
PBPK of Monoclonal Antibodies and Novel Modalities
Armin Sepp
|Certara, Sheffield, United Kindgom
Morning Short Course ‘Physiologically-based Pharmacokinetic (PBPK) Models: Basic Concepts to Advanced Applications’
Tuesday, June 13 - 14:00 - 16:30
Free Comms – Breaking Science
Co-chair: Rachel Rose
|Certara, Sheffield, United Kindgom
Plenary Session 3
Wednesday , June 14, 2023 - 10:00 - 12:00
Everyone Only Hears What S/He Understands
Amin Rostami-Hodjegan
|Certara, Sheffield, United Kindgom
June 11-14, 2023
“Modelling FcRn in Physiologically-Based Pharmacokinetics of Biologics: Mechanistic Approach to Bioavailability in Subcutaneously Dosing”
Armin Sepp
|Certara, Sheffield, United Kindgom
Poster
June 11-14, 2023
“Abundance of Renal Transporters in Healthy Caucasians: A Meta-Analysis.”
Matthew Harwood, Armin Sepp, Sibylle Neuhoff, and Mailys De Sousa Mendes
|Certara, Sheffield, United Kindgom
Poster
June 11-14, 2023
“Prediction of pH along the nephron tubule using the mechanistic kidney model (Mech KiM): Memantine as a case example.”
Liam Curry, Matthew Harwood, Frederic Bois, Sibylle Neuhoff, Mailys De Sousa Mendes
|Certara, Sheffield, United Kindgom
Poster
June 11-14, 2023
“Application of Physicologically Based Pharmacokinetic (PBPK) Moedlling for Prediction of Drug-Drug Interactions using the Strong CYP2D6 Inhibitor Terbinafine.”
Harry Moore, Kim Crewe, and Sibylle Neuhoff
|Certara, Sheffield, United Kindgom
Poster
June 11-14, 2023
“The Usefulness Of Combining Clinical Therapeutic Drug Monitoring Data With Bottom-up System Data To Understand The Effect Of Renal Impairment On The Non-renal Clearance Of Drugs: Tacrolimus As A Drug Example”
Eman El-Khateeb
|Certara, Sheffield, United Kindgom
Poster – (Finalist for Postdoctoral Poster Award)
June 11-14, 2023
“Dapagliflozin PBPK Compound File To Predict Changes In Its Exposure With Ddis, Various Ethnicities, And Special Disease Populations”
Eman El-Khateeb
|Certara, Sheffield, United Kindgom
Poster
June 11-14, 2023
“Evaluating the active contribution to creatinine renal clearance in renally impaired patients using PBPK modeling”
Olha Shuklinova and Sibylle Neuhoff
|Certara, Sheffield, United Kindgom
Poster