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Explore the World of Endogenous Biomarkers with Simcyp™!

Endogenous biomarkers play a pivotal role in comprehending drug-body interactions, shaping drug development, and propelling precision medicine forward. With our latest software release, the Simcyp™ Simulator introduces innovative features tailored to endogenous biomarkers.

In a comprehensive overview led by our expert presenter, Dr. Matthew Harwood, Principal Scientist in Translational DMPK, shares insights into:

  • Endogenous biomarker outputs, overlays, and parameter estimation templates
  • Available endogenous molecule files and their practical applications

Dr. Harwood covers a diverse range of topics, spanning from mechanistic models to the core principles of the simulator engine. Demonstrating workspace setup, outputs, and parameter estimation templates, he underscores:

  • The flexibility in synthesizing endogenous molecules
  • The crucial role of equilibration periods for precision in simulations
  • The seamless integration of endogenous markers in PK and DDI studies

Explore further insights on endogenous biomarkers in our latest blog post: