Excluding Venous Thromboembolism Using Point of Care D-dimer Tests in Outpatients: A Diagnostic Meta-analysis Publication Excluding Venous Thromboembolism Using Point of Care D-dimer Tests in Outpatients: A Diagnostic Meta-analysis This article is a review the evidence on the diagnostic accuracy of the currently available…CertaraAugust 14, 2009
On the Use of Change in Tumor Size to Predict Survival in Clinical Oncology Studies: Toward a New Paradigm to Design and Evaluate Phase 2 Studies Publication On the Use of Change in Tumor Size to Predict Survival in Clinical Oncology Studies: Toward a New Paradigm to Design and Evaluate Phase 2 Studies Drug-independent models that link biomarker response to clinical end points are critical to support early…CertaraAugust 1, 2009
Pharmacokinetic Analysis of Capsaicin After Topical Administration of a High-concentration Capsaicin Patch to Patients With Peripheral Neuropathic Pain Publication Pharmacokinetic Analysis of Capsaicin After Topical Administration of a High-concentration Capsaicin Patch to Patients With Peripheral Neuropathic Pain Capsaicin, a pungent compound in chili peppers, is a highly selective agonist for the transient…CertaraAugust 1, 2009
Population Pharmacokinetics of Intravenous Pantoprazole in Pediatric Intensive Care Patients Publication Population Pharmacokinetics of Intravenous Pantoprazole in Pediatric Intensive Care Patients What is already known about this subject The use of intravenous pantoprazole, a proton pump…CertaraFebruary 1, 2009
Pharmacokinetics, Safety, and Tolerability of Teduglutide, a Glucagon-like Peptide-2 (GLP-2) Analog, Following Multiple Ascending Subcutaneous Administrations in Healthy Subjects Publication Pharmacokinetics, Safety, and Tolerability of Teduglutide, a Glucagon-like Peptide-2 (GLP-2) Analog, Following Multiple Ascending Subcutaneous Administrations in Healthy Subjects Teduglutide, a glucagon-like peptide-2 (GLP-2) analog, is currently being evaluated for the treatment of short-bowel…CertaraNovember 1, 2008
Meta-analysis of the Diagnostic Accuracy of Transesophageal Echocardiography for Assessment of Atherosclerosis in the Ascending Aorta in Patients Undergoing Cardiac Surgery Publication Meta-analysis of the Diagnostic Accuracy of Transesophageal Echocardiography for Assessment of Atherosclerosis in the Ascending Aorta in Patients Undergoing Cardiac Surgery Stroke after cardiac surgery may be caused by emboli emerging from an atherosclerotic ascending aorta…CertaraOctober 1, 2008
Intestinal Metabolism and Transport of Drugs in Children: The Effects of Age and Disease Publication Intestinal Metabolism and Transport of Drugs in Children: The Effects of Age and Disease The presence of cytochrome P450 enzymes in the small bowel results in the reduced bioavailability…CertaraJuly 1, 2008
Pain Relief Model for a COX-2 Inhibitor in Patients with Postoperative Dental Pain Publication Pain Relief Model for a COX-2 Inhibitor in Patients with Postoperative Dental Pain The aim of this study was to develop a pain relief model for a cyclooxygenase…CertaraJuly 1, 2008
Development of CYP2D6 and CYP3A4 in the First Year of Life Publication Development of CYP2D6 and CYP3A4 in the First Year of Life Recently, Blake et al . ‘‘Ontogeny of dextromethorphan O- and N-demethylation in the first year…CertaraMay 1, 2008
CYP2D6 is Primarily Responsible for the Metabolism of Clomiphene Publication CYP2D6 is Primarily Responsible for the Metabolism of Clomiphene Clomiphene is a first line treatment for anovulation, a common cause of infertility. Response to…CertaraApril 30, 2008