Poster

Mechanistic Surface pH Modelling Improves PBPK Prediction of a Weakly Acidic Drug: Case Study of Bempedoic Acid

Explore how mechanistic surface pH modeling in Simcyp improves PBPK prediction of dissolution-controlled absorption for…

CertaraJune 26, 2026

Poster

Dermal PBPK Modelling of Propylparaben with a Novel Skin Metabolism Framework

Explore how a mechanistic dermal PBPK model with experimentally scaled, layer-specific skin metabolism predicts propylparaben…

CertaraJune 26, 2026

Poster

Application of PBPK Modelling to Explore Complex Food Effects on Trospium Chloride Pharmacokinetics

Discover how PBPK modeling with Simcyp mechanistically explains the formulation-dependent negative food effect of trospium…

CertaraJune 26, 2026

Poster

Cross-Version Simcyp Simulator Performance Assessment Using a Bioequivalence Framework for EMA Qualification

Learn how Certara used a bioequivalence-based TOST framework to demonstrate that Simcyp Simulator versions V20–V24…

CertaraJune 26, 2026

Poster

PBPK Modelling of Bispecific Monoclonal Antibody Tumour Targeting Specificity

Explore how PBPK modelling evaluates the in vivo tumour-targeting specificity of bispecific monoclonal antibodies (bsmAbs),…

CertaraJune 25, 2026

Poster

Sex-Specific Bioequivalence Outcomes: PBPK Insights into Gastric Emptying Variability

Discover how sex-dependent within-subject variability in gastric emptying time influences supersaturation, precipitation, and Cmax in…

CertaraJune 25, 2026

Poster

PBPK Modelling of Formulation-Dependent Food Effects for Itraconazole Oral Solution

Explore mechanistic PBPK modelling of itraconazole oral solution, revealing how bile salt–cyclodextrin interactions drive a…

CertaraJune 25, 2026

Poster

Integrating Endogenous Ligand Competition into a Mechanistic Whole-Body PBPK Model of Therapeutic Monoclonal Antibodies

Discover how endogenous ligand competition was incorporated into a whole-body PBPK model to improve prediction…

CertaraJune 23, 2026

Poster

Machine Learning based drug renal clearance predictor development and application

A machine learning QSAR model predicts human renal clearance from simple, easy-to-obtain inputs and sharpens…

CertaraJune 22, 2026

Brochure

2026 Simcyp Workshops

Advance your PBPK and model-informed drug development expertise with Simcyp workshops. Learn from experts through…

CertaraJune 11, 2026

Certara Products – Simcyp

Mechanistic Surface pH Modelling Improves PBPK Prediction of a Weakly Acidic Drug: Case Study of Bempedoic Acid

Dermal PBPK Modelling of Propylparaben with a Novel Skin Metabolism Framework

Application of PBPK Modelling to Explore Complex Food Effects on Trospium Chloride Pharmacokinetics

Cross-Version Simcyp Simulator Performance Assessment Using a Bioequivalence Framework for EMA Qualification

PBPK Modelling of Bispecific Monoclonal Antibody Tumour Targeting Specificity

Sex-Specific Bioequivalence Outcomes: PBPK Insights into Gastric Emptying Variability

PBPK Modelling of Formulation-Dependent Food Effects for Itraconazole Oral Solution

Integrating Endogenous Ligand Competition into a Mechanistic Whole-Body PBPK Model of Therapeutic Monoclonal Antibodies

Machine Learning based drug renal clearance predictor development and application

2026 Simcyp Workshops

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