Evaluating the efficiency of payload delivery by ADCs using a minimal PBPK model Poster Evaluating the efficiency of payload delivery by ADCs using a minimal PBPK model CertaraAugust 28, 2019
APPLICATION OF A MULTI-COMPARTMENT PERMEABILITY-LIMITED LUNG MODEL TO PREDICT LUNG CONCENTRATIONS OF MOXIFLOXACIN IN VIRTUAL HUMAN SUBJECTS Poster APPLICATION OF A MULTI-COMPARTMENT PERMEABILITY-LIMITED LUNG MODEL TO PREDICT LUNG CONCENTRATIONS OF MOXIFLOXACIN IN VIRTUAL HUMAN SUBJECTS CertaraAugust 28, 2019
Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis Poster Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis CertaraAugust 28, 2019
Application of mechanistic PBPK modelling to evaluate the power of pharmacogenomics studies using OATP1B1 and rosuvastatin as an example Poster Application of mechanistic PBPK modelling to evaluate the power of pharmacogenomics studies using OATP1B1 and rosuvastatin as an example CertaraAugust 28, 2019
APPLICATION OF PBPK AND BAYESIAN MODELLING FOR PREDICTION OF THE LIKELIHOOD OF INDIVIDUAL PATIENTS EXPERIENCING SERIOUS ADVERSE REACTIONS TO A STANDARD DOSE OF EFAVIRENZ Poster APPLICATION OF PBPK AND BAYESIAN MODELLING FOR PREDICTION OF THE LIKELIHOOD OF INDIVIDUAL PATIENTS EXPERIENCING SERIOUS ADVERSE REACTIONS TO A STANDARD DOSE OF EFAVIRENZ CertaraAugust 28, 2019
DEVELOPMENT OF A PBPK MODEL FOR EFAVIRENZ THAT ACCOUNTS FOR AUTO-INDUCTION AND ITS EFFECT ON THE CYP2B6 SUBSTRATE BUPROPION Poster DEVELOPMENT OF A PBPK MODEL FOR EFAVIRENZ THAT ACCOUNTS FOR AUTO-INDUCTION AND ITS EFFECT ON THE CYP2B6 SUBSTRATE BUPROPION CertaraAugust 23, 2019
Prediction of Midazolam Pharmacokinetics in Pregnant Women with Coeliac Disease using Simcyp Pregnancy PBPK Model Poster Prediction of Midazolam Pharmacokinetics in Pregnant Women with Coeliac Disease using Simcyp Pregnancy PBPK Model CertaraAugust 23, 2019
Investigating Impacts of Model Parameters Correlations in Global Sensitivity Analysis: Determining the Most Influential Parameters of a Minimal PBPK Model of Midazolam Poster Investigating Impacts of Model Parameters Correlations in Global Sensitivity Analysis: Determining the Most Influential Parameters of a Minimal PBPK Model of Midazolam CertaraJune 24, 2019
PBPK’s Pivotal Role in Modern Drug Development: Busting Common Myths and Misconceptions White Paper PBPK’s Pivotal Role in Modern Drug Development: Busting Common Myths and Misconceptions This white paper addresses common PBPK myths and misconceptions and demonstrates how this approach is…CertaraFebruary 4, 2019
Using PBPK Models to Assess Fetal Drug Exposure Blog Using PBPK Models to Assess Fetal Drug Exposure The tragedy of thalidomide provides a cautionary tale about the potential for birth defects resulting…CertaraJanuary 19, 2018