Prediction of Liver Volume—A Population-based Approach to Meta-analysis of Pediatric, Adult, and Geriatric Populations—An Update Publication Prediction of Liver Volume—A Population-based Approach to Meta-analysis of Pediatric, Adult, and Geriatric Populations—An Update —CertaraMarch 1, 2017
The Absorption Kinetics of Ketoconazole Plays a Major Role in Explaining the Reported Variability in the Level of Interaction with Midazolam: Interplay Between Formulation and Inhibition of Gut Wall and Liver Metabolism Publication The Absorption Kinetics of Ketoconazole Plays a Major Role in Explaining the Reported Variability in the Level of Interaction with Midazolam: Interplay Between Formulation and Inhibition of Gut Wall and Liver Metabolism CertaraFebruary 1, 2017
The Pharmacokinetics of Transdermal Flunixin Meglumine in Holstein Calves Publication The Pharmacokinetics of Transdermal Flunixin Meglumine in Holstein Calves This study describes the pharmacokinetics of topical and intravenous (IV) flunixin meglumine in Holstein calves.…CertaraDecember 1, 2016
Quantifying Gut Wall Metabolism: Methodology Matters Publication Quantifying Gut Wall Metabolism: Methodology Matters CertaraDecember 1, 2016
Pharmacokinetics of Oral Terbinafine in Adult Horses Publication Pharmacokinetics of Oral Terbinafine in Adult Horses The primary study objective was to compare the pharmacokinetics of p.o. terbinafine alone to p.o.…CertaraNovember 24, 2016
Vaccination Mitigates the Impact of PRRSv Infection on the Pharmacokinetics of Ceftiofur Crystalline-free Acid in Pigs Publication Vaccination Mitigates the Impact of PRRSv Infection on the Pharmacokinetics of Ceftiofur Crystalline-free Acid in Pigs The pharmacokinetics of intramuscularly administered ceftiofur crystalline-free acid (CCFA) were determined in pigs that were…CertaraNovember 24, 2016
Early Assessment of Proarrhythmic Risk of Drugs Using the In Vitro Data and Single-cell-based In Silico Models: Proof of Concept Publication Early Assessment of Proarrhythmic Risk of Drugs Using the In Vitro Data and Single-cell-based In Silico Models: Proof of Concept CertaraNovember 23, 2016
A Study to Examine the Relationship Between Metritis Severity and Depletion of Oxytetracycline in Plasma and Milk after Intrauterine Infusion Publication A Study to Examine the Relationship Between Metritis Severity and Depletion of Oxytetracycline in Plasma and Milk after Intrauterine Infusion Metritis is a frequent problem in postpartum dairy cows. Intrauterine therapy with the antimicrobial oxytetracycline…CertaraOctober 1, 2016
Phase 1 Study Assessing the Pharmacokinetic Profile and Safety of Avibactam in Patients with Renal Impairment Publication Phase 1 Study Assessing the Pharmacokinetic Profile and Safety of Avibactam in Patients with Renal Impairment Avibactam is a non-β-lactam β-lactamase inhibitor intended for use as a fixed-dose combination with ceftazidime…CertaraJuly 12, 2016
A Tutorial on Pharmacodynamic Scripting Facility in Simcyp Publication A Tutorial on Pharmacodynamic Scripting Facility in Simcyp The Simcyp® Simulator provides a framework for mechanistic Physiologically-Based Pharmacokinetic/Pharmacodynamic modelling of potentially interacting drugs.…CertaraJuly 9, 2016