Population Pharmacokinetics of Azithromycin in Whole Blood, Peripheral Blood Mononuclear Cells, and Polymorphonuclear Cells in Healthy Adults
Azithromycin's extensive distribution to proinflammatory cells, including peripheral blood mononuclear cells (PBMCs) and polymorphonuclear cells…
CertaraMarch 5, 2014
Pharmacokinetic and Pharmacodynamic Modeling to Determine the Human Dose of ST-246(R) to Protect Against Smallpox
Although smallpox has been eradicated, the United States government considers it a "material threat" and…
CertaraMarch 1, 2013
Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an In Vitro-In Vivo Extrapolation Model
The pharmacokinetics (PK) of efavirenz (EFV) is characterized by marked inter-patient variability that correlates with…
CertaraOctober 1, 2012
