A Mechanistic PK/PD Model for First-in-Human Dosing of a Tetraspecific Antibody (MDX2001) for the Treatment of Advanced Solid Tumors Poster A Mechanistic PK/PD Model for First-in-Human Dosing of a Tetraspecific Antibody (MDX2001) for the Treatment of Advanced Solid Tumors MDX2001 is a tetraspecific T cell engager that binds CD3 and CD28 on T cells…CertaraNovember 22, 2024
Model-Informed Drug Development Framework for the Development and Dose Optimization of Targeted Radiation Therapies Poster Model-Informed Drug Development Framework for the Development and Dose Optimization of Targeted Radiation Therapies CertaraNovember 22, 2024
Augmented Definitive Screening Design Provides Efficient Phase 1 Selection of CAR T-cell and Lymphodepletion Regimen Poster Augmented Definitive Screening Design Provides Efficient Phase 1 Selection of CAR T-cell and Lymphodepletion Regimen CertaraNovember 22, 2024
Oncology MIDD Simulator, A User-Friendly Application for Overall Survival Forecasting in Early Oncology Trials Poster Oncology MIDD Simulator, A User-Friendly Application for Overall Survival Forecasting in Early Oncology Trials CertaraNovember 22, 2024
Quantitative Systems Pharmacology model for combined targeting of BAFF and CD40 pathways in systemic lupus erythematosus Poster Quantitative Systems Pharmacology model for combined targeting of BAFF and CD40 pathways in systemic lupus erythematosus CertaraNovember 22, 2024
Population pharmacokinetic modeling of niraparib to assess different absorption models Poster Population pharmacokinetic modeling of niraparib to assess different absorption models CertaraNovember 22, 2024
A Medical Writer’s Guide to Collaborative Authoring Blog A Medical Writer’s Guide to Collaborative Authoring Once upon a time, regulatory writing for drug development programs followed a scheduled routine and…CertaraNovember 22, 2024
Real-world application of physiologically based pharmacokinetic models in drug discovery Publication Real-world application of physiologically based pharmacokinetic models in drug discovery The utility of physiologically based pharmacokinetic (PBPK) models in support of drug development has been…CertaraNovember 22, 2024
Top Three Insights from Certainty Europe Blog Top Three Insights from Certainty Europe The first European Certainty Conference for the Certara Client Community in Mainz Germany was full…CertaraNovember 21, 2024
Expert Insights into Early Drug Development Video Expert Insights into Early Drug Development CertaraNovember 21, 2024