The Pharmacokinetics of Transdermal Flunixin Meglumine in Holstein Calves Publication The Pharmacokinetics of Transdermal Flunixin Meglumine in Holstein Calves This study describes the pharmacokinetics of topical and intravenous (IV) flunixin meglumine in Holstein calves.…CertaraDecember 1, 2016
Limitations of MIC as Sole Metric of Pharmacodynamic Response Across the Range of Antimicrobial Susceptibilities within a Single Bacterial Species Publication Limitations of MIC as Sole Metric of Pharmacodynamic Response Across the Range of Antimicrobial Susceptibilities within a Single Bacterial Species The minimum inhibitory concentration (MIC) of an antimicrobial drug for a bacterial pathogen is used…CertaraDecember 1, 2016
Modeling and Experimental Studies of Obeticholic Acid Exposure and the Impact of Cirrhosis Stage Publication Modeling and Experimental Studies of Obeticholic Acid Exposure and the Impact of Cirrhosis Stage CertaraDecember 1, 2016
Pinnacle 21 Wins TOPRA Award for Regulatory Excellence in Innovation Announcement Pinnacle 21 Wins TOPRA Award for Regulatory Excellence in Innovation Certara’s Pinnacle 21 is honored to announce that Max Kanevsky, has been named to the…CertaraDecember 1, 2016
Quantifying Gut Wall Metabolism: Methodology Matters Publication Quantifying Gut Wall Metabolism: Methodology Matters CertaraDecember 1, 2016
Pharmacokinetics of Oral Terbinafine in Adult Horses Publication Pharmacokinetics of Oral Terbinafine in Adult Horses The primary study objective was to compare the pharmacokinetics of p.o. terbinafine alone to p.o.…CertaraNovember 24, 2016
Vaccination Mitigates the Impact of PRRSv Infection on the Pharmacokinetics of Ceftiofur Crystalline-free Acid in Pigs Publication Vaccination Mitigates the Impact of PRRSv Infection on the Pharmacokinetics of Ceftiofur Crystalline-free Acid in Pigs The pharmacokinetics of intramuscularly administered ceftiofur crystalline-free acid (CCFA) were determined in pigs that were…CertaraNovember 24, 2016
Early Assessment of Proarrhythmic Risk of Drugs Using the In Vitro Data and Single-cell-based In Silico Models: Proof of Concept Publication Early Assessment of Proarrhythmic Risk of Drugs Using the In Vitro Data and Single-cell-based In Silico Models: Proof of Concept CertaraNovember 23, 2016
A Randomized Dose Escalation Study of Intravenous Baclofen in Healthy Volunteers: Clinical Tolerance and Pharmacokinetics Publication A Randomized Dose Escalation Study of Intravenous Baclofen in Healthy Volunteers: Clinical Tolerance and Pharmacokinetics CertaraNovember 17, 2016
Impact of Target-mediated Elimination on the Dose and Regimen of Evolocumab, a Human Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Publication Impact of Target-mediated Elimination on the Dose and Regimen of Evolocumab, a Human Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) CertaraNovember 15, 2016