Skip to main content
search
Total and Free Blood and Plasma Concentration Changes in Pregnancy for Medicines Highly Bound to Plasma Proteins: Application of Physiologically Based Pharmacokinetic Modelling to Understand the Impact on Efficacy Publication

Total and Free Blood and Plasma Concentration Changes in Pregnancy for Medicines Highly Bound to Plasma Proteins: Application of Physiologically Based Pharmacokinetic Modelling to Understand the Impact on Efficacy

For drugs highly bound to plasma proteins, changes in concentrations of free drug may have…
Certara
January 3, 2024
Off-Target Drug Safety: Replacing Educated Guesswork with Evidence-Based Risk Assessment On-Demand Webinar

Off-Target Drug Safety: Replacing Educated Guesswork with Evidence-Based Risk Assessment

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 integrates safety and toxicology software to address three critical areas in preclinical safety: Cardiac…
Certara
December 19, 2023
First-In-Human (FIH) Faster: The Power of Physiologically Based Pharmacokinetic (PBPK) Modeling On-Demand Webinar

First-In-Human (FIH) Faster: The Power of Physiologically Based Pharmacokinetic (PBPK) Modeling

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 Advanced Strategies and Best Practices for Predictive Pharmacokinetics using Simcyp™ Discovery   Refine your…
Certara
December 13, 2023