Real-world application of PBPK in drug discovery Publication Real-world application of PBPK in drug discovery The utility of PBPK models in support of drug development has been well documented. During…CertaraJanuary 11, 2024
Industrializing Quantitative Systems Pharmacology (QSP): Why now and how. On-Demand Webinar Industrializing Quantitative Systems Pharmacology (QSP): Why now and how. What does it take to industrialize QSP? What is the right mix of technology and…CertaraJanuary 9, 2024
MedCity News | How the IRA Has Created a New Environment for Biosimilars Press Coverage MedCity News | How the IRA Has Created a New Environment for Biosimilars By Maximillian Vargas and Caitlin Verrilli As IRA provisions are activated, the law’s impact on…CertaraJanuary 5, 2024
Clinical Research News | Trendspotting: What’s Coming for Clinical Trials and Research in 2024 Press Coverage Clinical Research News | Trendspotting: What’s Coming for Clinical Trials and Research in 2024 By Clinical Research Team We spoke with leaders and experts in the Clinical Research community…CertaraJanuary 5, 2024
Bio-IT World | Trendspotting: What’s Coming for Biotech in 2024 Press Coverage Bio-IT World | Trendspotting: What’s Coming for Biotech in 2024 By Bio-IT World Team To kick off the New Year, we spoke with leaders and…CertaraJanuary 5, 2024
Physiologically Based Pharmacokinetic modelling of drugs in pregnancy: A mini-review on availability and limitations Publication Physiologically Based Pharmacokinetic modelling of drugs in pregnancy: A mini-review on availability and limitations This mini-review provides a concise and comprehensive overview of the pregnancy PBPK field and identify…CertaraJanuary 3, 2024
A Literature Review of Changes in Phase II Drug-Metabolizing Enzyme and Drug Transporter Expression during Pregnancy Publication A Literature Review of Changes in Phase II Drug-Metabolizing Enzyme and Drug Transporter Expression during Pregnancy This comprehensive review exposes gaps in current knowledge of phase II enzyme and drug transporter…CertaraJanuary 3, 2024
Total and Free Blood and Plasma Concentration Changes in Pregnancy for Medicines Highly Bound to Plasma Proteins: Application of Physiologically Based Pharmacokinetic Modelling to Understand the Impact on Efficacy Publication Total and Free Blood and Plasma Concentration Changes in Pregnancy for Medicines Highly Bound to Plasma Proteins: Application of Physiologically Based Pharmacokinetic Modelling to Understand the Impact on Efficacy For drugs highly bound to plasma proteins, changes in concentrations of free drug may have…CertaraJanuary 3, 2024
Bridging the Gap: Integrating Pharmacometrics with Quantitative Systems Pharmacology (QSP) for Smoother Clinical Phase Transitions On-Demand Webinar Bridging the Gap: Integrating Pharmacometrics with Quantitative Systems Pharmacology (QSP) for Smoother Clinical Phase Transitions Master clinical phase transitions with insights from industry leaders! Join Piet van der Graaf, SVP…CertaraJanuary 2, 2024