Using Modeling & Simulation to Develop a Dosing Regimen for a Bispecific Antibody for Pediatric Cancer Case Study Using Modeling & Simulation to Develop a Dosing Regimen for a Bispecific Antibody for Pediatric Cancer Bispecific antibodies are an emerging class of antibodies developed in recent years that provide new…CertaraJanuary 23, 2023
Leveraging Clinical Data from One Rare Disease to Support Drug Approval for Another Case Study Leveraging Clinical Data from One Rare Disease to Support Drug Approval for Another Atypical hemolytic uremic syndrome (aHUS) is an ultra-rare genetic disease that causes abnormal blood clot…CertaraJune 1, 2022
Dose Optimization Using Population PK for an Orphan Drug Case Study Dose Optimization Using Population PK for an Orphan Drug RAPALIMUS® Tablets (sirolimus) is Nobelpharma’s orphan drug developed from an oral medication that is sold…CertaraNovember 17, 2021
Arming adherence-based drug development with pharmacometrics Blog Arming adherence-based drug development with pharmacometrics The time is right to explore how sensor-enabled digital adherence monitoring systems can benefit patients,…CertaraSeptember 12, 2016
Back to the future (of pharmacometrics) with Dr. Lawrence Lesko Blog Back to the future (of pharmacometrics) with Dr. Lawrence Lesko Pharmacometrics uses mathematical models of biology, pharmacology, disease, and physiology to describe and quantify interactions…CertaraDecember 1, 2015