Efficient Phase 1 Selection of CAR-T and Lymphodepletion Regimens Using Augmented Definitive Screening Design
How an augmented definitive screening design identified CAR-T and lymphodepletion regimens with 2.37-fold higher odds…
CertaraNovember 20, 2024
Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women
The article "Recent Applications of Pharmacometrics and Systems Pharmacology Approaches to Improve and Optimize Drug…
CertaraNovember 18, 2024
Population Pharmacokinetics of Tamibarotene in Pediatric and Young Adult Patients with Recurrent or Refractory Solid Tumors
Find out how PopPK modelling supports precise tamibarotene dosing in pediatric and young adult solid…
CertaraNovember 14, 2024
Enhancing Pharmacokinetics Workflows at Charles River
PreclinicalPhoenix™ Integral Data Repository Charles River, a global leader in drug development, sought to improve…
CertaraNovember 13, 2024
Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody
The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…
CertaraNovember 4, 2024
Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women
The article titled "Using PBPK modeling to supplement clinical data and support the safe and…
CertaraOctober 30, 2024
Bioequivalence Analysis of Ondansetron Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Two-Period Crossover Phase I Study
Explore how ondansetron formulations are bioequivalent under fasting and fed conditions, confirmed using Phoenix WinNonlin.
CertaraOctober 29, 2024
