Poster

Integrating Endogenous Ligand Competition into a Mechanistic Whole-Body PBPK Model of Therapeutic Monoclonal Antibodies

Discover how endogenous ligand competition was incorporated into a whole-body PBPK model to improve prediction…

CertaraJune 23, 2026

Poster

Application of IO Simulator in Immuno-Oncology Combination Therapy: A Small Cell Lung Cancer Case Study

Learn how Certara's IO Simulator was used to predict efficacy, cytokine release syndrome risk, and…

CertaraJune 23, 2026

Poster

Mechanistic Modelling of CRS in T-cell Engagers – An Application for Blinatumomab

Discover how Quantitative Systems Pharmacology (QSP) was used to predict cytokine release syndrome risk and…

CertaraJune 23, 2026

Poster

Machine Learning-Based Covariate Selection for Population Pharmacokinetic Modeling

Authors: Ibtissem Rebai (Certara), Stephen Duffull (Certara), Ayman Akil (Certara), Anna Largajolli (Certara), Floris Fauchet…

CertaraJune 22, 2026

Poster

Shaping the future of AI/ML in pharmacometrics through collaboration, education and best practices

Discover how the AI/ML Special Interest Group is advancing responsible artificial intelligence in pharmacometrics through…

CertaraJune 22, 2026

Poster

Machine Learning based drug renal clearance predictor development and application

A machine learning QSAR model predicts human renal clearance from simple, easy-to-obtain inputs and sharpens…

CertaraJune 22, 2026

Poster

Accelerating QSP Virtual Population Generation Through Active Learning and Bayesian Optimization

Discover how active learning and Bayesian optimization improve virtual population generation for quantitative systems pharmacology…

CertaraJune 18, 2026

Poster

Mechanistic QSP Modeling to Support KIT Inhibitor Dose Selection, Biomarker Strategy, and Clinical Development

Discover how a mechanistic quantitative systems pharmacology (QSP) model predicts mast cell inhibition and depletion…

CertaraJune 16, 2026

Blog

Data, Models, and Modalities: Key Themes from the Certainty 2026 Discovery UGM

A recap of the Certainty 2026 Discovery UGM in Boston, covering the top themes from…

CertaraJune 15, 2026

Live Events

Mechanistic MIDD: Achieving Regulatory Success Through Strong Scientific Foundations

June 30, 2026 - 12:00 PM – 2:00 PM

CertaraJune 10, 2026

Model Informed Drug Development

Integrating Endogenous Ligand Competition into a Mechanistic Whole-Body PBPK Model of Therapeutic Monoclonal Antibodies

Application of IO Simulator in Immuno-Oncology Combination Therapy: A Small Cell Lung Cancer Case Study

Mechanistic Modelling of CRS in T-cell Engagers – An Application for Blinatumomab

Machine Learning-Based Covariate Selection for Population Pharmacokinetic Modeling

Shaping the future of AI/ML in pharmacometrics through collaboration, education and best practices

Machine Learning based drug renal clearance predictor development and application

Accelerating QSP Virtual Population Generation Through Active Learning and Bayesian Optimization

Mechanistic QSP Modeling to Support KIT Inhibitor Dose Selection, Biomarker Strategy, and Clinical Development

Data, Models, and Modalities: Key Themes from the Certainty 2026 Discovery UGM

Mechanistic MIDD: Achieving Regulatory Success Through Strong Scientific Foundations

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